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  • Primary Antibodies ›
  • Galectin 3 Antibodies

Invitrogen

Galectin 3 Monoclonal Antibody (GT759)

View all (131) Galectin 3 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Galectin 3 Monoclonal Antibody (GT759)

  • Antibody Testing Data (2)
Galectin 3 Antibody in ELISA (ELISA)
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Galectin 3 Antibody in ELISA (ELISA)
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Galectin 3 Antibody (MA5-50299) in ELISA

Sandwich ELISA of Galectin 3 in recombinant full-length Galectin 3 protein. Samples were incubated with Galectin 3 monoclonal antibody (Product # MA5-50299) using a dilution of 5 µg/mL (capture) and Galectin 3 polyclonal antibody (Product # PA5-34819) as detection antibody at concentration of 1 µg/mL. Followed by Rabbit IgG antibody (HRP) at a dilution of 1:10,000. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Galectin 3 Antibody in Western Blot (WB)
Galectin 3 Antibody in ELISA (ELISA)

Product Details

MA5-50299

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:3,000
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

GT759

Immunogen

Recombinant protein encompassing a sequence within the center region of human Galectin 3. The exact sequence is proprietary.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.66 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3091357

Product Specific Information

This product can be used in Sandwich ELISA to detect Galectin 3 using MA5-50299 as a capture antibody and PA5-34819 as the detection antibody.

Target Information

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 35 kDa lectin; advanced glycation end-product receptor 3; Carbohydrate-binding protein 35; CBP 35; CBP-30; Gal-3; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; Galectin-3; Galectin3; IgE-binding protein; L-29; L-31; Laminin-binding protein; Lectin L-29; lectin, galactoside-binding, soluble, 3; MAC-2 antigen

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Gene Aliases: CBP35; GAL3; GALBP; GALIG; L31; LGALS2; LGALS3; MAC2

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UniProt ID: (Human) P17931

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Entrez Gene ID: (Human) 3958

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Function(s)
protein binding IgE binding carbohydrate binding chemoattractant activity laminin binding poly(A) RNA binding
Process(es)
monocyte chemotaxis mRNA processing RNA splicing neutrophil chemotaxis epithelial cell differentiation regulation of T cell proliferation innate immune response negative regulation of endocytosis eosinophil chemotaxis macrophage chemotaxis negative regulation of T cell receptor signaling pathway positive chemotaxis regulation of T cell apoptotic process mononuclear cell migration positive regulation of mononuclear cell migration positive regulation of calcium ion import regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of immunological synapse formation negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell positive regulation of dendritic cell differentiation negative regulation of extrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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