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  • Galectin 3 Antibodies

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Galectin 3 Polyclonal Antibody

View all (131) Galectin 3 antibodies

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Datasheet
Protocols
Questions & Answers

Cite Galectin 3 Polyclonal Antibody

  • Antibody Testing Data (1)
Galectin 3 Antibody in Western Blot (WB)
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Galectin 3 Antibody in Western Blot (WB)
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Galectin 3 Antibody (BS-20699R) in WB

Human MCF-7 lysates probed with Galectin 3 Polyclonal Antibody, Unconjugated (bs-20699R) at 1:300 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37°C. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Galectin 3 Antibody in Western Blot (WB)
Galectin 3 Polyclonal Antibody

Product Details

BS-20699R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300
-

Flow Cytometry (Flow)

1:20-1:100
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Galectin 3, amino acids 121-200.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C

Shipping conditions

Wet ice

Target Information

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 35 kDa lectin; advanced glycation end-product receptor 3; Carbohydrate-binding protein 35; CBP 35; CBP-30; Gal-3; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; Galectin-3; Galectin3; IgE-binding protein; L-29; L-31; Laminin-binding protein; Lectin L-29; lectin, galactoside-binding, soluble, 3; MAC-2 antigen

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Gene Aliases: CBP35; GAL3; GALBP; GALIG; L31; LGALS2; LGALS3; MAC2

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UniProt ID: (Human) P17931

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Entrez Gene ID: (Human) 3958

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Function(s)
protein binding IgE binding carbohydrate binding chemoattractant activity laminin binding poly(A) RNA binding
Process(es)
monocyte chemotaxis mRNA processing RNA splicing neutrophil chemotaxis epithelial cell differentiation regulation of T cell proliferation innate immune response negative regulation of endocytosis eosinophil chemotaxis macrophage chemotaxis negative regulation of T cell receptor signaling pathway positive chemotaxis regulation of T cell apoptotic process mononuclear cell migration positive regulation of mononuclear cell migration positive regulation of calcium ion import regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of immunological synapse formation negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell positive regulation of dendritic cell differentiation negative regulation of extrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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