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Invitrogen

GSR Recombinant Rabbit Monoclonal Antibody (23GB2845)

Advanced Verification
View all (18) GSR antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite GSR Recombinant Rabbit Monoclonal Antibody (23GB2845)

  • Antibody Testing Data (3)
  • Advanced Verification (1)
GSR Antibody in Immunocytochemistry (ICC/IF)
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GSR Antibody in Immunocytochemistry (ICC/IF)
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GSR Antibody (MA5-53478) in ICC/IF

Immunocytochemistry analysis of GSR in HeLa cells. Nuclei were stained blue with DAPI; GSR recombinant monoclonal antibody (Product # MA5-53478) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Very low. Scale bar: 20 μm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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GSR Antibody in Immunocytochemistry (ICC/IF)
GSR Antibody in Western Blot (WB)
GSR Antibody in Flow Cytometry (Flow)
GSR Antibody
GSR Recombinant Rabbit Monoclonal Antibody (23GB2845)

Product Details

MA5-53478

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:5,000
-

Immunocytochemistry (ICC/IF)

1:1,000
-

Flow Cytometry (Flow)

1:2,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293F

Class

Recombinant Monoclonal

Type

Antibody

Clone

23GB2845

Immunogen

A synthesized peptide derived from human GLUR (470-522AA).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3247949

Target Information

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: epididymis luminal protein 75; epididymis secretory sperm binding protein Li 122m; glutathione reductase; glutathione reductase 1; Glutathione reductase, mitochondrial; glutathione S-reductase; GR; GRase

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Gene Aliases: AI325518; D8Ertd238e; GLUR; Gr-1; Gr1; GRD1; GSR; HEL-75; HEL-S-122m

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UniProt ID: (Human) P00390, (Mouse) P47791

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Entrez Gene ID: (Human) 2936, (Mouse) 14782

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Function(s)
glutathione-disulfide reductase activity electron carrier activity flavin adenine dinucleotide binding NADP binding oxidoreductase activity oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor protein homodimerization activity glutathione binding
Process(es)
response to reactive oxygen species glutathione metabolic process nucleobase-containing small molecule interconversion cell redox homeostasis oxidation-reduction process cellular oxidant detoxification spermatogenesis
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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