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Invitrogen

GPI Polyclonal Antibody

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Cite GPI Polyclonal Antibody

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GPI Antibody
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GPI Antibody
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GPI Antibody (PA5-84103)

Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of GPI was observed specifically in A-549 cells and in SK-MEL-30 cells using anti-GPI Polyclonal Antibody (Product # PA5-84103) in western blot. The relative expression levels of GPI within each cell line is shown using RNA-Seq. {R... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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GPI Antibody
GPI Polyclonal Antibody

Product Details

PA5-84103

Applications
Tested Dilution
Publications

Western Blot (WB)

0.04-0.4 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GPI. Recombinant protein control fragment (Product #RP-104938).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791255

Product Specific Information

Immunogen sequence: VINIGIGGSD LGPLMVTEAL KPYSSGGPRV WYVSNIDGTH IAKTLAQLNP ESSLFIIASK TFTTQETITN AETAKEWFLQ AAKDPSAVAK HFVALST

Target Information

This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AMF; Autocrine motility factor; glucose phosphate isomerase; Glucose-6-phosphate isomerase; GPI; hexose monophosphate isomerase; hexosephosphate isomerase; Neuroleukin; NLK; oxoisomerase; PGI; PHI; Phosphoglucose isomerase; phosphohexomutase; Phosphohexose isomerase; phosphosaccharomutase; SA-36; sperm antigen; Sperm antigen 36; sperm antigen-36

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Gene Aliases: AMF; GNPI; GPI; NLK; PGI; PHI; SA-36; SA36

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UniProt ID: (Human) P06744

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Entrez Gene ID: (Human) 2821

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Function(s)
glucose-6-phosphate isomerase activity cytokine activity growth factor activity intramolecular transferase activity ubiquitin protein ligase binding monosaccharide binding
Process(es)
angiogenesis in utero embryonic development mesoderm formation carbohydrate metabolic process gluconeogenesis humoral immune response hemostasis learning or memory methylglyoxal biosynthetic process erythrocyte homeostasis glucose homeostasis negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of neuron apoptotic process aldehyde catabolic process glucose 6-phosphate metabolic process canonical glycolysis
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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