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Invitrogen
GNAO1 Polyclonal Antibody
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FIGURE: 1 / 1
GNAO1 Antibody (PA5-97796) in WB
Product Details
PA5-97796
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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RRID
Target Information
Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: DKFZp686O0962; G alpha o; GNAO 1; Go alpha; GTP-binding protein alpha o; GTP-binding protein alpha-o subunit; guanine nucleotide binding protein, alpha O polypeptide 1; Guanine nucleotide-binding protein G(o) subunit alpha
Gene Aliases: alphaO; AW050213; Galphao; Gna0; Gnao; Gnao1; RATBPGTPC
UniProt ID: (Rat) P59215, (Mouse) P18872
Entrez Gene ID: (Rat) 50664, (Mouse) 14681
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