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Invitrogen
GM2A Polyclonal Antibody
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FIGURE: 1 / 5
GM2A Antibody (PA5-115302) in ICC/IF
Product Details
PA5-115302
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
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Shipping conditions
RRID
Product Specific Information
Antibody detects endogenous levels of total GM2A.
Target Information
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Cerebroside sulfate activator protein; Ganglioside GM2 activator; GM2 ganglioside activator protein; GM2-AP; SAP-3; shingolipid activator protein 3; Sphingolipid activator protein 3
Gene Aliases: AA408702; AW215435; GM2-AP; GM2A; SAP-3
UniProt ID: (Human) P17900, (Mouse) Q60648
Entrez Gene ID: (Human) 2760, (Mouse) 14667, (Rat) 282838
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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