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GDF2 Monoclonal Antibody (4D2)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite GDF2 Monoclonal Antibody (4D2)

  • Antibody Testing Data (1)
GDF2 Antibody in ELISA (ELISA)
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GDF2 Antibody in ELISA (ELISA)
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GDF2 Antibody (H00002658-M01) in ELISA

Detection limit for recombinant GST tagged GDF2 is approximately 0.3 ng/mL as a capture antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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GDF2 Antibody in ELISA (ELISA)
GDF2 Monoclonal Antibody (4D2)

Product Details

H00002658-M01

Applications
Tested Dilution
Publications

ELISA (ELISA)

0.3 ng/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

4D2

Immunogen

GDF2 (NP_057288, 320 a.a. approximately 419 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: SAGAGSHCQK TSLRVNFEDI GWDSWIIAPK EYEAYECKGG CFFPLADDVT PTKHAIVQTL VHLKFPTKVG KACCVPTKLS PISVLYKDDM GVPTLKYHYE

Target Information

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: BMP; BMP-9; Bone morphogenetic protein; Bone morphogenetic protein 9; GDF-2; Growth/differentiation factor 2

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Gene Aliases: BMP-9; BMP9; GDF2; HHT5

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UniProt ID: (Human) Q9UK05

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Entrez Gene ID: (Human) 2658

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Function(s)
cytokine activity transforming growth factor beta receptor binding protein binding growth factor activity
Process(es)
ossification angiogenesis patterning of blood vessels vasculogenesis osteoblast differentiation negative regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation cellular iron ion homeostasis negative regulation of DNA replication negative regulation of endothelial cell migration positive regulation of pathway-restricted SMAD protein phosphorylation negative regulation of angiogenesis negative regulation of cell growth BMP signaling pathway positive regulation of BMP signaling pathway positive regulation of interleukin-8 production activin receptor signaling pathway growth regulation of apoptotic process regulation of MAPK cascade negative regulation of blood vessel endothelial cell migration positive regulation of endothelial cell differentiation positive regulation of osteoblast differentiation positive regulation of angiogenesis positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter cell development blood vessel morphogenesis cartilage development pathway-restricted SMAD protein phosphorylation SMAD protein signal transduction positive regulation of cartilage development cellular response to BMP stimulus negative regulation of DNA biosynthetic process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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