Invitrogen

GATA6 Monoclonal Antibody (6H8)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers
GATA6 Monoclonal Antibody (6H8)

Product Details

MA5-32961

Applications
Tested Dilution
Publications

Western Blot (WB)

1:200-1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Monoclonal

Type

Antibody

Clone

6H8

Immunogen

Recombinant full length Human GATA-6.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2802595

Product Specific Information

Purity is > 95% by SDS-PAGE.

Target Information

GATA6 is thought to be important for regulating terminal differentiation and/or proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ASD9; AVSD5; GATA-binding factor 6; Transcription factor GATA-6

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Gene Aliases: GATA6

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UniProt ID: (Human) Q92908

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Entrez Gene ID: (Human) 2627

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Function(s)
RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor binding RNA polymerase II repressing transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding zinc ion binding protein kinase binding transcription regulatory region DNA binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter in utero embryonic development liver development outflow tract septum morphogenesis type B pancreatic cell differentiation pancreatic A cell differentiation transcription from RNA polymerase II promoter phospholipid metabolic process endodermal cell fate determination blood coagulation male gonad development cardiac muscle hypertrophy in response to stress positive regulation of BMP signaling pathway negative regulation of transforming growth factor beta1 production negative regulation of transforming growth factor beta2 production tube morphogenesis response to drug negative regulation of apoptotic process response to estrogen cellular protein metabolic process cell fate commitment positive regulation of angiogenesis negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter cell development organ formation smooth muscle cell differentiation positive regulation of cardioblast differentiation cardiac muscle cell differentiation positive regulation of cardiac muscle cell proliferation lung saccule development Clara cell differentiation Type II pneumocyte differentiation intestinal epithelial cell differentiation cardiac vascular smooth muscle cell differentiation response to growth factor positive regulation of cell cycle arrest cellular response to gonadotropin stimulus cellular response to hypoxia cellular response to BMP stimulus
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