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  • GALR1 Antibodies

Invitrogen

GALR1 Recombinant Rabbit Monoclonal Antibody (18H2L18)

View all (10) GALR1 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite GALR1 Recombinant Rabbit Monoclonal Antibody (18H2L18)

  • Antibody Testing Data (4)
GALR1 Antibody in Immunocytochemistry (ICC/IF)
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GALR1 Antibody in Immunocytochemistry (ICC/IF)
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GALR1 Antibody (703803) in ICC/IF

HEK-293 cells transiently transfected with GALR1 were grown on poly-L-lysine-coated coverslips overnight. After 24 h, cells were fixed with 4% paraformaldehyde and 0.2% picric acid in phosphate buffer (pH 6.9) for 30 min at room temperature and washed several times with phosphate buffer. Specimens were permeabilized with ice-cold methanol and then incubated with Anti-GALR1 Recombinant Rabbit Monoclonal Antibody (Product # 703803, 1:500 dilution). Cells were then incubated with Alexa488-conjugated secondary antibody for 2 h at room temperat... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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GALR1 Antibody in Immunocytochemistry (ICC/IF)
GALR1 Antibody in Immunohistochemistry (IHC)
GALR1 Antibody in Immunohistochemistry (IHC)
GALR1 Antibody in Western Blot (WB)
GALR1 Recombinant Rabbit Monoclonal Antibody (18H2L18)

Product Details

703803

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

Immunohistochemistry (IHC)

1:500
-

Immunocytochemistry (ICC/IF)

1:500
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Expression System

Expi293

Class

Recombinant Monoclonal

Type

Antibody

Clone

18H2L18

Immunogen

Peptides corresponding to human GALR1 [1) aa329-aa349 2) aa14-aa32]
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2866473

Product Specific Information

This antibody is predicted to react with Mouse, Bovine.

Target Information

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Gal receptor 1; Gal-1 receptor; Gal-r1; GAL1-R; Galanin r1 receptor; Galanin receptor type 1; Galanin-1 receptor; Galn1r; GALR-1; Hugal 1-r

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Gene Aliases: GALNR; GALNR1; GALR1

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UniProt ID: (Human) P47211, (Rat) Q62805

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Entrez Gene ID: (Human) 2587, (Rat) 50577

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Function(s)
galanin receptor activity protein binding peptide hormone binding neuropeptide binding
Process(es)
adenylate cyclase-modulating G-protein coupled receptor signaling pathway adenylate cyclase-activating G-protein coupled receptor signaling pathway negative regulation of adenylate cyclase activity phospholipase C-activating G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration neuropeptide signaling pathway digestion positive regulation of transcription from RNA polymerase II promoter positive regulation of cortisol secretion G-protein coupled receptor signaling pathway
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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