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GABPA Monoclonal Antibody (4B8-G6)

View all (19) GABPA antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite GABPA Monoclonal Antibody (4B8-G6)

  • Antibody Testing Data (4)
GABPA Antibody in ELISA (ELISA)
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GABPA Antibody in ELISA (ELISA)
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GABPA Antibody (H00002551-M01) in ELISA

Detection limit for recombinant GST tagged GABPA is approximately 0.03 ng/mL as a capture antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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GABPA Antibody in Immunocytochemistry (ICC/IF)
GABPA Antibody in Western Blot (WB)
GABPA Antibody in Western Blot (WB)
GABPA Antibody in ELISA (ELISA)
GABPA Monoclonal Antibody (4B8-G6)

Product Details

H00002551-M01

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

Immunocytochemistry (ICC/IF)

10 µg/mL
-

ELISA (ELISA)

0.03 ng/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

4B8-G6

Immunogen

GABPA (AAH35031, 1 a.a. approximately 454 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MTKREAEELI EIEIDGTEKA ECTEESIVEQ TYAPAECVSQ AIDINEPIGN LKKLLEPRLQ CSLDAHEICL QDIQLDPERS LFDQGVKTDG TVQLSVQVIS YQGIEPKLNI LEIVKPADTV EVVIDPDAHH AESEAHLVEE AQVITLDGTK HITTISDETS EQVTRWAAAL EGYRKEQERL GIPYDPIQWS TDQVLHWVVW VMKEFSMTDI DLTTLNISGR ELCSLNQEDF FQRVPRGEIL WSHLELLRKY VLASQEQQMN EIVTIDQPVQ IIPASVQSAT PTTIKVINSS AKAAKVQRAP RISGEDRSSP GNRTGNNGQI QLWQFLLELL TDKDARDCIS WVGDEGEFKL NQPELVAQKW GQRKNKPTMN YEKLSRALRY YYDGDMICKV QGKRFVYKFV CDLKTLIGYS AAELNRLVTE CEQKKLAKMQ LHGIAQPVTA VALSTASLQT EKDN

Target Information

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: GA binding protein transcription factor alpha subunit 60kDa; GA binding protein transcription factor, alpha subunit 60kDa; GA-binding protein alpha chain; GABP subunit alpha; human nuclear respiratory factor-2 subunit alpha; nuclear respiratory factor 2 alpha subunit; Nuclear respiratory factor 2 subunit alpha; Transcription factor E4TF1-60

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Gene Aliases: E4TF1-60; E4TF1A; GABPA; NFT2; NRF2; NRF2A; RCH04A07

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UniProt ID: (Human) Q06546

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Entrez Gene ID: (Human) 2551

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Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription regulatory region DNA binding protein heterodimerization activity
Process(es)
negative regulation of transcription from RNA polymerase II promoter in utero embryonic development transcription from RNA polymerase II promoter mitochondrion organization cell differentiation negative regulation of megakaryocyte differentiation positive regulation of transcription from RNA polymerase II promoter
It has to be done as per old AB suggested Products section.
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