Huabio

G6PD Polyclonal Antibody

Name: G6PD Polyclonal Antibody
Brand: Huabio
SKU: R1706-7

View all (37) G6PD antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (8)

G6PD Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 8

G6PD Antibody (R1706-7) in ICC/IF

ICC staining G6PD in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS.

G6PD Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Immunogen image

Immunogen Image G6PD Polyclonal Antibody

Product Details

R1706-7

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Immunocytochemistry (ICC/IF)

1:50-1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein within human G6PD aa 218-404.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 0.2% BSA, 50% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Target Information

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: G6PD; Glucose-6-phosphate 1-dehydrogenase; Glucose-6-phosphate 1-dehydrogenase X; glucose-6-phosphate dehydrogenase X-linked

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Gene Aliases: G28A; G6PD; G6pd-1; G6PD1; G6pdx; Gpdx

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UniProt ID: (Human) P11413, (Rat) P05370, (Mouse) Q00612

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Entrez Gene ID: (Human) 2539, (Rat) 24377, (Mouse) 14381

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Function(s)

glucose-6-phosphate dehydrogenase activity protein binding glucose binding identical protein binding protein homodimerization activity NADP binding carbohydrate binding oxidoreductase activity

Process(es)

glucose metabolic process pentose-phosphate shunt lipid metabolic process cholesterol biosynthetic process NADP metabolic process NADPH regeneration glutathione metabolic process pentose-phosphate shunt, oxidative branch negative regulation of protein glutathionylation response to organic cyclic compound pentose biosynthetic process substantia nigra development response to food cellular response to oxidative stress erythrocyte maturation regulation of neuron apoptotic process response to ethanol ribose phosphate biosynthetic process glucose 6-phosphate metabolic process oxidation-reduction process cytokine production angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure vasodilation by angiotensin involved in regulation of systemic arterial blood pressure carbohydrate metabolic process NADP biosynthetic process response to oxidative stress interleukin-10 production interleukin-12 production regulation of multicellular organism growth erythrocyte development

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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G6PD Polyclonal Antibody

G6PD Antibody (R1706-7) in ICC/IF

Product Details

R1706-7

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Target Information

References (0)

Bioinformatics

Performance Guarantee

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