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  • G6PD Antibodies

Invitrogen

G6PD Polyclonal Antibody

View all (37) G6PD antibodies

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Datasheet
Protocols
Questions & Answers

Cite G6PD Polyclonal Antibody

  • Antibody Testing Data (4)
G6PD Antibody in Western Blot (WB)
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G6PD Antibody in Western Blot (WB)
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G6PD Antibody (PA5-145333) in WB

Western blot analysis of G6PD in Mouse Lung lysate. Samples were incubated with G6PD polyclonal antibody (Product # PA5-145333) using a dilution of 2 µg/mL followed by HRP-Linked Caprine Anti-Rabbit IgG secondary antibody at a dilution of 0.2 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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G6PD Antibody in Western Blot (WB)
G6PD Antibody in Western Blot (WB)
G6PD Antibody in Western Blot (WB)
G6PD Antibody in Western Blot (WB)
G6PD Polyclonal Antibody

Product Details

PA5-145333

Applications
Tested Dilution
Publications

Western Blot (WB)

0.2-2 µg/mL
-
Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Rat G6PD protein, Met1-Leu515 (Accession #P05370)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% Proclin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3093556

Target Information

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: G6PD; Glucose-6-phosphate 1-dehydrogenase; Glucose-6-phosphate 1-dehydrogenase X; glucose-6-phosphate dehydrogenase X-linked

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Gene Aliases: G28A; G6pd; G6pd-1; G6pdx; Gpdx

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UniProt ID: (Rat) P05370, (Mouse) Q00612

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Entrez Gene ID: (Rat) 24377, (Mouse) 14381

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Function(s)
glucose-6-phosphate dehydrogenase activity glucose binding carbohydrate binding identical protein binding protein homodimerization activity NADP binding oxidoreductase activity
Process(es)
cytokine production angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure vasodilation by angiotensin involved in regulation of systemic arterial blood pressure carbohydrate metabolic process glucose metabolic process pentose-phosphate shunt cholesterol biosynthetic process NADP metabolic process NADPH regeneration NADP biosynthetic process glutathione metabolic process response to oxidative stress pentose-phosphate shunt, oxidative branch negative regulation of protein glutathionylation pentose biosynthetic process interleukin-10 production interleukin-12 production cellular response to oxidative stress regulation of multicellular organism growth erythrocyte maturation regulation of neuron apoptotic process response to ethanol ribose phosphate biosynthetic process erythrocyte development glucose 6-phosphate metabolic process oxidation-reduction process response to organic cyclic compound substantia nigra development response to food
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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