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Proteintech
Frizzled 7 Polyclonal Antibody
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Product Details
16974-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: QPYHGEKGI SVPDHGFCQP ISIPLCTDIA YNQTILPNLL GHTNQEDAGL EVHQFYPLVK VQCSPELRFF LCSMYAPVCT VLDQAIPPCR SLCERARQGC EALMNKFGFQ WPERLRCENF PVHGAGEICV GQNTSDGSGG PGGGPTAYPT APYLPDLPFT ALPPGASDGR GRPAFPFSCP RQLKVPPYLG YRFLGERDCG APCEPGRANG LMYFKEEERR FARLWV (33-257 aa encoded by BC015915)
Target Information
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: frizzled 7, seven transmembrane spanning receptor; frizzled family receptor 7; frizzled homolog 7; Frizzled, drosophila, homolog of, 7; Frizzled-7; Fz-7; FzE3; hFz7; mFz7; rizzled 7
Gene Aliases: Fz7; FZD7; FzE3
UniProt ID: (Human) O75084, (Mouse) Q61090
Entrez Gene ID: (Human) 8324, (Mouse) 14369
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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