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  • Ferroportin Antibodies

Invitrogen

Ferroportin Polyclonal Antibody

Advanced Verification
2 Published Figures
3 References
View all (11) Ferroportin antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Ferroportin Polyclonal Antibody

  • Antibody Testing Data (6)
  • Published Figures (2)
  • Advanced Verification (1)
Ferroportin Antibody in Immunocytochemistry (ICC/IF)
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Ferroportin Antibody in Immunocytochemistry (ICC/IF)
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Ferroportin Antibody (PA5-64232) in ICC/IF

Immunofluorescent staining of SLC40A1 in human cell line U-2 OS using a SLC40A1 Polyclonal Antibody (Product # PA5-64232) shows localization to plasma membrane and cytosol. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Ferroportin Antibody in Immunocytochemistry (ICC/IF)
Ferroportin Antibody in Immunohistochemistry (IHC)
Ferroportin Antibody in Immunohistochemistry (IHC)
Ferroportin Antibody in Immunohistochemistry (IHC)
Ferroportin Antibody in Immunohistochemistry (IHC)
Ferroportin Antibody in Western Blot (WB)
Ferroportin Antibody in Western Blot (WB)
Ferroportin Antibody in Western Blot (WB)
Ferroportin Antibody
Ferroportin Polyclonal Antibody

Product Details

PA5-64232

Applications
Tested Dilution
Publications

Western Blot (WB)

1µg/mL
View 2 publications 2 publications

Immunohistochemistry (IHC)

-
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500
-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SLC40A1. Recombinant protein control fragment (Product #RP-104220).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.41 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2647507

Product Specific Information

Immunogen sequence: VKAGLKEEET ELKQLNLHKD TEPKPLEGTH LMGVKDSNIH ELEHEQEPTC ASQMAEPFRT FRDGWVSYYN

Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 86%.

Target Information

SLC40A1 is an iron-regulated transporter assumed to play roles in intestinal iron absorption and cellular iron release. It mediates iron efflux in the presence of ferroxidase. Defects in SLC40A1 cause hemochromatosis type 4 (HFE4), which is an autosomal dominant iron-loading disorder.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Ferroportin; Ferroportin-1; iron regulated gene 1; Iron-regulated transporter 1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; solute carrier family 40 (iron-regulated transporter), member 1; Solute carrier family 40 member 1

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Gene Aliases: FPN; FPN1; HFE4; IREG1; MST079; MSTP079; MTP1; SLC11A3; SLC40A1

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UniProt ID: (Human) Q9NP59

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Entrez Gene ID: (Human) 30061

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Function(s)
receptor activity iron ion transmembrane transporter activity protein binding ferrous iron transmembrane transporter activity peptide hormone binding iron channel activity
Process(es)
lymphocyte homeostasis endothelium development cellular iron ion homeostasis regulation of transcription from RNA polymerase II promoter in response to iron iron ion transmembrane transport negative regulation of apoptotic process positive regulation of transcription from RNA polymerase II promoter spleen trabecula formation multicellular organismal iron ion homeostasis ferrous iron export
It has to be done as per old AB suggested Products section.
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