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  • Ferroportin Antibodies

Invitrogen

Ferroportin Polyclonal Antibody

View all (11) Ferroportin antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Ferroportin Polyclonal Antibody

  • Antibody Testing Data (2)
Ferroportin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Ferroportin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 2

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Ferroportin Antibody (PA5-115915) in IHC (P)

Immunohistochemistry analysis of Ferroportin in human colorectal cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115915) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Ferroportin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Ferroportin Antibody in Western Blot (WB)
Ferroportin Polyclonal Antibody

Product Details

PA5-115915

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human SLC40A1(Accession Q9NP59), corresponding to amino acid residues G12-A62.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2900549

Product Specific Information

Antibody detects endogenous levels of total SLC40A1.

Target Information

SLC40A1 is an iron-regulated transporter assumed to play roles in intestinal iron absorption and cellular iron release. It mediates iron efflux in the presence of ferroxidase. Defects in SLC40A1 cause hemochromatosis type 4 (HFE4), which is an autosomal dominant iron-loading disorder.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CAR1; Cell adhesion regulator; duodenal-specific; Ferroportin; ferroportin 1; Ferroportin-1; iron regulated gene 1; Iron-regulated transporter 1; Metal transporter protein 1; metal transporting protein 1; MTP1; polycythaemia; SLC11A3 iron transporter; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; solute carrier family 39 (iron-regulated transporter), member 1; solute carrier family 40 (iron-regulated transporter), member 1; Solute carrier family 40 member 1

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Gene Aliases: Dusg; FPN; FPN1; Fpt1; HFE4; IREG1; MST079; MSTP079; MTP; MTP1; Ol5; Pcm; SLC11A3; Slc39a1; SLC40A1

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UniProt ID: (Human) Q9NP59, (Mouse) Q9JHI9, (Rat) Q923U9

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Entrez Gene ID: (Human) 30061, (Mouse) 53945, (Rat) 170840

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Function(s)
receptor activity iron ion transmembrane transporter activity protein binding ferrous iron transmembrane transporter activity peptide hormone binding iron channel activity
Process(es)
lymphocyte homeostasis endothelium development cellular iron ion homeostasis regulation of transcription from RNA polymerase II promoter in response to iron iron ion transmembrane transport negative regulation of apoptotic process positive regulation of transcription from RNA polymerase II promoter spleen trabecula formation multicellular organismal iron ion homeostasis ferrous iron export transport ion transport iron ion transport spleen development iron ion homeostasis ferrous iron transmembrane transport
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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