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NeoBiotechnologies

Fascin-1 (Reed-Sternberg Cell Marker) Monoclonal Antibody (FSCN1/417)

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Datasheet
Protocols
Questions & Answers

Cite Fascin-1 (Reed-Sternberg Cell Marker) Monoclonal Antibody (FSCN1/417)

  • Antibody Testing Data (7)
Fascin-1 (Reed-Sternberg Cell Marker) Antibody in Immunocytochemistry (ICC/IF)
Group 53 Created with Sketch.
Fascin-1 (Reed-Sternberg Cell Marker) Antibody in Immunocytochemistry (ICC/IF)
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Fascin-1 (Reed-Sternberg Cell Marker) Antibody (6624-MSM2-P0) in ICC/IF

Immunofluorescence analysis of HeLa cells labeling Fascin with Fascin-1 Mouse Monoclonal Antibody (FSCN1/417)-CF640 (Green). The nuclear counterstain is Hoechst (Blue). Membrane is Phalloidin 488 (Red) . {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Fascin-1 (Reed-Sternberg Cell Marker) Antibody in Immunocytochemistry (ICC/IF)
Fascin-1 (Reed-Sternberg Cell Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Fascin-1 (Reed-Sternberg Cell Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Fascin-1 (Reed-Sternberg Cell Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Fascin-1 (Reed-Sternberg Cell Marker) Antibody in Western Blot (WB)
Fascin-1 (Reed-Sternberg Cell Marker) Antibody in Flow Cytometry (Flow)
Fascin-1 (Reed-Sternberg Cell Marker) Antibody in SDS-PAGE (SDS-PAGE)
Fascin-1 (Reed-Sternberg Cell Marker) Monoclonal Antibody (FSCN1/417)

Product Details

6624-MSM2-P0

Applications
Tested Dilution
Publications

Western Blot (WB)

1-2 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL
-

Immunocytochemistry (ICC/IF)

1-2 µg/mL
-

Flow Cytometry (Flow)

1-2 µg/10^6 cells
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

FSCN1/417

Immunogen

Full length recombinant human FSCN1 protein
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Wet ice

Target Information

Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; Fascin; Fascin homolog 1; fascin homolog 1, actin-bundling protein; Fascin1; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); Singed-like protein

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Gene Aliases: FAN1; FSCN1; HSN; p55; SNL

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UniProt ID: (Human) Q16658

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Entrez Gene ID: (Human) 6624

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Function(s)
actin binding protein binding drug binding protein binding, bridging poly(A) RNA binding actin filament binding cadherin binding involved in cell-cell adhesion
Process(es)
cell-cell junction assembly cell proliferation anatomical structure morphogenesis positive regulation of lamellipodium assembly cell migration microspike assembly actin cytoskeleton organization regulation of microvillus assembly regulation of actin cytoskeleton organization establishment of apical/basal cell polarity cell motility actin filament bundle assembly positive regulation of filopodium assembly positive regulation of podosome assembly positive regulation of extracellular matrix disassembly cell-cell adhesion
It has to be done as per old AB suggested Products section.
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