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  • Primary Antibodies ›
  • FZR1 Antibodies

Invitrogen

FZR1 Polyclonal Antibody

View all (10) FZR1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite FZR1 Polyclonal Antibody

  • Antibody Testing Data (7)
FZR1 Antibody in Immunocytochemistry (ICC/IF)
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FZR1 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 7

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FZR1 Antibody (PA5-85303) in ICC/IF

Immunocytochemistry analysis of FZR1 in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Samples were incubated with FZR1 polyclonal antibody (Product # PA5-85303) using a dilution of 1:500 (green). Red: Phalloidin, a cytoskeleton marker, diluted at 1:100. Scale bar = 10 μm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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FZR1 Antibody in Immunocytochemistry (ICC/IF)
FZR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FZR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FZR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FZR1 Antibody in Western Blot (WB)
FZR1 Antibody in Western Blot (WB)
FZR1 Antibody in Western Blot (WB)

Product Details

PA5-85303

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:3,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000
-

Immunocytochemistry (ICC/IF)

1:100-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human FZR1. The exact sequence is proprietary.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.26 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 20% glycerol, 1% BSA

Contains

0.025% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2792446

Product Specific Information

Keep as concentrated solution.

Predicted reactivity: Mouse (95%), Rat (95%), Xenopus laevis (90%), Pig (97%), Chicken (94%), Rhesus Monkey (100%), Bovine (97%).

Positive Control: A431, A431 nuclear extract.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

FZR is a 7WD domain family member implicated in cell cycle regulation of Drosophila and yeast. It has been shown that the over expression of fzr proteins increases natural killer cell-mediated cell death and as a result, suppresses tumor growth. The fzr protein is essential for cyclosome activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CDC20 homolog 1; CDC20-like 1b; CDC20-like protein 1; Cdh1/Hct1 homolog; cell division cycle 20 related 1; Fizzy-related protein homolog; Fzr; hCDH1

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Gene Aliases: AW108046; CDC20C; CDH1; FYR; FZR; FZR1; FZR2; HCDH; HCDH1; KIAA1242

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UniProt ID: (Human) Q9UM11, (Mouse) Q9R1K5

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Entrez Gene ID: (Human) 51343, (Mouse) 56371, (Rat) 314642

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Function(s)
protein binding anaphase-promoting complex binding ubiquitin-protein transferase activator activity
Process(es)
DNA repair mitotic nuclear division positive regulation of cell proliferation anaphase-promoting complex-dependent catabolic process G2 DNA damage checkpoint regulation of meiotic nuclear division protein ubiquitination involved in ubiquitin-dependent protein catabolic process positive regulation of protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle lens fiber cell differentiation protein K11-linked ubiquitination negative regulation of cell aging positive regulation of ubiquitin protein ligase activity cellular response to DNA damage stimulus cell cycle
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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