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  • Primary Antibodies ›
  • FZD4 Antibodies

Invitrogen

FZD4 Polyclonal Antibody

View all (13) FZD4 antibodies

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Protocols
Questions & Answers

Cite FZD4 Polyclonal Antibody

  • Antibody Testing Data (7)
FZD4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FZD4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 7

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FZD4 Antibody (PA5-33556) in IHC (P)

Immunohistochemistry analysis of FZD4 in human Skin, Melanoma. Samples were incubated with FZD4 polyclonal antibody (Product # PA5-33556). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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FZD4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FZD4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FZD4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FZD4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FZD4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FZD4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FZD4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FZD4 Polyclonal Antibody

Product Details

PA5-33556

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

25 µg/mL
-
Product Specifications

Species Reactivity

Bat, Bovine, Dog, Chicken, Horse, Hamster, Human, Mouse, Non-human primate, Pig, Rabbit, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 13 amino acid peptide from C-terminus of human FZD4 / Frizzled 4.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550936

Target Information

FZD4 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Frizzled 4 is widely expressed, particularly in heart, skeletal muscle, ovary, and fetal kidney. Transcripts have also been identified in liver, kidney, pancreas, spleen, and fetal lung, and in smaller amounts in placenta, adult lung, prostate, testis, colon, and fetal brain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD344; CD344 antigen; cFz-4; frizzled 4, seven transmembrane spanning receptor; frizzled class receptor 4; frizzled family receptor 4; frizzled homolog 4; frizzled receptor 4; Frizzled-4; frizzled-4-like; frizzled-4-like protein; Fz-4; FzE4; mFz4; MGC34390; rFz4; WNT receptor frizzled-4

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Gene Aliases: BOS_24395; CD344; EVR1; FEVR; Frizzled-4; FZ-4; FZ4; FZD4; FZD4S; FzE4; GPCR; hFz4; I79_022172

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UniProt ID: (Human) Q9ULV1, (Chicken) Q9IA05, (Mouse) Q61088, (Rat) Q9QZH0

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Entrez Gene ID: (Dog) 485149, (Human) 8322, (Bovine) 445416, (Chicken) 373887, (Mouse) 14366, (Chinese hamster) 100756296, (Rat) 64558, (Rabbit) 100342099

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Function(s)
G-protein coupled receptor activity protein binding Wnt-protein binding cytokine binding PDZ domain binding ubiquitin protein ligase binding protein homodimerization activity Wnt-activated receptor activity protein heterodimerization activity signal transducer activity transmembrane signaling receptor activity
Process(es)
luteinization blood vessel development vasculogenesis signal transduction cell surface receptor signaling pathway G-protein coupled receptor signaling pathway Wnt signaling pathway, calcium modulating pathway multicellular organism development sensory perception of sound negative regulation of cell-substrate adhesion Wnt signaling pathway regulation of vascular endothelial growth factor receptor signaling pathway locomotion involved in locomotory behavior substrate adhesion-dependent cell spreading extracellular matrix-cell signaling non-canonical Wnt signaling pathway progesterone secretion positive regulation of JUN kinase activity positive regulation of transcription, DNA-templated positive regulation of sequence-specific DNA binding transcription factor activity canonical Wnt signaling pathway retina vasculature morphogenesis in camera-type eye cerebellum vasculature morphogenesis retinal blood vessel morphogenesis neuron differentiation Wnt signaling pathway, planar cell polarity pathway cellular response to retinoic acid biological_process brain development embryo development
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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