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  • FLAP Antibodies

Invitrogen

FLAP Polyclonal Antibody

Advanced Verification
View all (10) FLAP antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite FLAP Polyclonal Antibody

  • Antibody Testing Data (2)
  • Advanced Verification (1)
FLAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FLAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FLAP Antibody (PA5-82926) in IHC (P)

Immunohistochemical analysis of FLAP in human skeletal muscle using FLAP Polyclonal Antibody (Product # PA5-82926) shows low expression as expected. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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FLAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FLAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FLAP Antibody
FLAP Polyclonal Antibody

Product Details

PA5-82926

Applications
Tested Dilution
Publications

Western Blot (WB)

0.04-0.4 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ALOX5AP. Recombinant protein control fragment (Product #RP-89567).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2790082

Product Specific Information

Immunogen sequence: HKVEHESRTQ NGRSFQRTGT LAFERVYTAN QNCVDAYPTF LAVL

Target Information

ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Arachidonate 5-lipoxygenase-activating protein; FLAP; MK-886-binding protein

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Gene Aliases: ALOX5AP; FLAP

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UniProt ID: (Human) P20292

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Entrez Gene ID: (Human) 241

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Function(s)
glutathione transferase activity leukotriene-C4 synthase activity glutathione peroxidase activity protein binding enzyme activator activity protein N-terminus binding arachidonic acid binding
Process(es)
leukotriene metabolic process leukotriene biosynthetic process lipoxygenase pathway positive regulation of catalytic activity protein homotrimerization cellular response to calcium ion lipoxin metabolic process
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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