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Proteintech
FGL2 Polyclonal Antibody
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Product Details
11827-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Product Specific Information
Immunogen sequence: MKLANWYWL SSAVLAAYGF LVVANNETEE IKDERAKDVC PVRLESRGKC EEAGECPYQV SLPPLTIQLP KQFSRIEEVF KEVQNLKEIV NSLKKSCQDC KLQADDNGDP GRNGLLLPST GAPGEVGDNR VRELESEVNK LSSELKFIF (1-148 aa encoded by BC017813 )
Target Information
Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role, such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively expressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: associated with MHV-3 induced prothrombinase activity; Cytotoxic T-lymphocyte-specific protein; fibrinogen-like 2; Fibrinogen-like protein 2; Fibroleukin; Prothrombinase; pT49
Gene Aliases: AI385601; FGL2; Fiblp; musfiblp; pT49; T49
UniProt ID: (Human) Q14314, (Mouse) P12804
Entrez Gene ID: (Human) 10875, (Mouse) 14190, (Rat) 84586
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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