FGFR2 Monoclonal Antibody (OTI1D3), TrueMAB™

protein tyrosine kinase activity fibroblast growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding heparin binding 1-phosphatidylinositol-3-kinase activity fibroblast growth factor binding protein homodimerization activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity

negative regulation of transcription from RNA polymerase II promoter MAPK cascade angiogenesis ureteric bud development in utero embryonic development epithelial to mesenchymal transition positive regulation of mesenchymal cell proliferation outflow tract septum morphogenesis membranous septum morphogenesis apoptotic process cell-cell signaling axonogenesis positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway regulation of smoothened signaling pathway post-embryonic development embryonic pattern specification organ morphogenesis regulation of cell fate commitment positive regulation of phospholipase activity regulation of phosphatidylinositol 3-kinase signaling morphogenesis of embryonic epithelium peptidyl-tyrosine phosphorylation orbitofrontal cortex development ventricular zone neuroblast division pyramidal neuron development gland morphogenesis positive regulation of Wnt signaling pathway bone mineralization lung development epithelial cell differentiation midbrain development otic vesicle formation hair follicle morphogenesis lacrimal gland development regulation of osteoblast proliferation multicellular organism growth organ growth fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow fibroblast growth factor receptor signaling pathway involved in hemopoiesis fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development phosphatidylinositol-3-phosphate biosynthetic process regulation of multicellular organism growth regulation of fibroblast growth factor receptor signaling pathway inner ear morphogenesis odontogenesis positive regulation of MAPK cascade positive regulation of GTPase activity cell fate commitment regulation of osteoblast differentiation positive regulation of cell cycle positive regulation of transcription from RNA polymerase II promoter protein autophosphorylation phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling lung alveolus development mesodermal cell differentiation embryonic digestive tract morphogenesis embryonic organ morphogenesis digestive tract development embryonic organ development reproductive structure development positive regulation of smooth muscle cell proliferation embryonic cranial skeleton morphogenesis skeletal system morphogenesis epidermis morphogenesis branching morphogenesis of a nerve mesenchymal cell differentiation positive regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation regulation of smooth muscle cell differentiation positive regulation of cell division ventricular cardiac muscle tissue morphogenesis positive regulation of cardiac muscle cell proliferation limb bud formation bone development bone morphogenesis branching involved in prostate gland morphogenesis branching involved in salivary gland morphogenesis bud elongation involved in lung branching lung lobe morphogenesis lung-associated mesenchyme development positive regulation of epithelial cell proliferation involved in lung morphogenesis prostate gland morphogenesis prostate epithelial cord elongation prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis squamous basal epithelial stem cell differentiation involved in prostate gland acinus development fibroblast growth factor receptor signaling pathway involved in mammary gland specification lateral sprouting from an epithelium mammary gland bud formation epithelial cell proliferation involved in salivary gland morphogenesis branch elongation involved in salivary gland morphogenesis branching involved in labyrinthine layer morphogenesis regulation of branching involved in prostate gland morphogenesis regulation of morphogenesis of a branching structure mesenchymal cell differentiation involved in lung development mesenchymal cell proliferation involved in lung development regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of canonical Wnt signaling pathway