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  • FAP Antibodies

Invitrogen

FAP Recombinant Rabbit Monoclonal Antibody (5H0Y9)

View all (32) FAP antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite FAP Recombinant Rabbit Monoclonal Antibody (5H0Y9)

  • Antibody Testing Data (3)
FAP Antibody in Immunocytochemistry (ICC/IF)
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FAP Antibody in Immunocytochemistry (ICC/IF)
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FAP Antibody (MA5-51530) in ICC/IF

Immunocytochemistry of FAP in NIH/3T3 cells. Samples were incubated with FAP Recombinant monoclonal antibody (Product # MA5-51530) using a dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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FAP Antibody in Immunocytochemistry (ICC/IF)
FAP Antibody in Immunocytochemistry (ICC/IF)
FAP Antibody in Western Blot (WB)
FAP Recombinant Rabbit Monoclonal Antibody (5H0Y9)

Product Details

MA5-51530

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

5H0Y9

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 411-510 of human FAP (NP_004451.2).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.82 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3093758

Product Specific Information

Immunogen sequence: SSNEFEEYPG RRNIYRISIG SYPPSKKCVT CHLRKERCQY YTASFSDYAK YYALVCYGPG IPISTLHDGR TDQEIKILEE NKELENALKN IQLPKEEIKK

Target Information

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; FAPalpha; Fibroblast activation protein alpha; fibroblast activation protein, alpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; Prolyl endopeptidase FAP; Seprase; Serine integral membrane protease; SIMP; Surface-expressed protease

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Gene Aliases: DPPIV; FAP; FAPA; SIMP

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UniProt ID: (Human) Q12884, (Mouse) P97321

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Entrez Gene ID: (Human) 2191, (Rat) 192203, (Mouse) 14089

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Function(s)
protease binding endopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity integrin binding protein binding peptidase activity serine-type peptidase activity dipeptidyl-peptidase activity protein homodimerization activity protein dimerization activity hydrolase activity
Process(es)
proteolysis regulation of collagen catabolic process negative regulation of extracellular matrix disassembly endothelial cell migration proteolysis involved in cellular protein catabolic process negative regulation of cell proliferation involved in contact inhibition positive regulation of cell cycle arrest mitotic cell cycle arrest melanocyte proliferation positive regulation of execution phase of apoptosis melanocyte apoptotic process negative regulation of extracellular matrix organization angiogenesis cell adhesion regulation of fibrinolysis apoptotic process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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