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  • Primary Antibodies ›
  • EphA1 Antibodies

Fabgennix

Ephrin Receptor A1 Polyclonal Antibody, Biotin

View all (29) EphA1 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Ephrin Receptor A1 Polyclonal Antibody, Biotin

Ephrin Receptor A1 Polyclonal Antibody, Biotin

Product Details

EPHAR1-BIOTIN

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken within amino acid region 55-605 on human Ephrin type-A receptor 1.
View immunogen

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

EphA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA1 is expressed in some human cancer cell lines and has been implicated in carcinogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: EPH tyrosine kinase; EPH tyrosine kinase 1; Ephrin type-A receptor 1; erythropoietin-producing hepatoma amplified sequence; Erythropoietin-producing hepatoma receptor; hEpha1; MGC163163; oncogene EPH; soluble EPHA1 variant 1; soluble EPHA1 variant 2; Tyrosine-protein kinase receptor EPH

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Gene Aliases: EPH; EPHA1; EPHT; EPHT1

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UniProt ID: (Human) P21709

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Entrez Gene ID: (Human) 2041

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Function(s)
protein kinase activity transmembrane-ephrin receptor activity ATP binding protein kinase binding
Process(es)
angiogenesis positive regulation of cell-matrix adhesion negative regulation of protein kinase activity cell surface receptor signaling pathway positive regulation of cell proliferation peptidyl-tyrosine phosphorylation positive regulation of cell migration negative regulation of cell migration substrate adhesion-dependent cell spreading somatic stem cell population maintenance regulation of GTPase activity positive regulation of angiogenesis protein autophosphorylation ephrin receptor signaling pathway positive regulation of stress fiber assembly activation of GTPase activity
It has to be done as per old AB suggested Products section.
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