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  • Eotaxin 2 Antibodies

Invitrogen

Eotaxin 2 Monoclonal Antibody (106521)

View all (16) Eotaxin 2 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Eotaxin 2 Monoclonal Antibody (106521)

  • Antibody Testing Data (1)
Eotaxin 2 Antibody in Neutralization (Neu)
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Eotaxin 2 Antibody in Neutralization (Neu)
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Eotaxin 2 Antibody (MA5-23851) in Neu

Neutralization of Eotaxin 2 in BaF3 mouse pro‚B cell line transfected with mouse CCR3. Samples were incubated in Eotaxin 2 monoclonal antibody (Product # MA5-23851). Recombinant Mouse CCL24/Eotaxin‚2 chemoattracts the BaF3 mouse pro‚B cell line transfected with mouse CCR3 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin. Chemotaxis elicited by Recombinant Mouse CCL24/Eotaxin‚2 (20 ng/mL) is neutralized (green line) by increasing concentrations of R... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Eotaxin 2 Antibody in Neutralization (Neu)
Eotaxin 2 Monoclonal Antibody (106521)

Product Details

MA5-23851

Applications
Tested Dilution
Publications

Western Blot (WB)

1 µg/mL
-

ELISA (ELISA)

0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture)
-

Neutralization (Neu)

0.06-0.3 µg/mL
-
Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rat / IgG2a

Class

Monoclonal

Type

Antibody

Clone

106521

Immunogen

E. coli-derived recombinant mouse CCL24/Eotaxin-2/MPIF-2 Ile24-Val119
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2577145

Product Specific Information

Reconstitute at 0.5 mg/mL in sterile PBS.

Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: C-C motif chemokine 24; CC chemokine CCL24; Eosinophil chemotactic protein 2; Eotaxin-2; Eotaxin2; small inducible cytokine A24; Small-inducible cytokine A24

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Gene Aliases: Ccl24; CKb-6; MPIF-2; Scya24

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UniProt ID: (Mouse) Q9JKC0

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Entrez Gene ID: (Mouse) 56221

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Function(s)
cytokine activity chemokine activity
Process(es)
positive regulation of endothelial cell proliferation chemotaxis inflammatory response immune response cytoskeleton organization regulation of cell shape positive regulation of cell migration positive regulation of actin filament polymerization positive regulation of GTPase activity positive regulation of angiogenesis eosinophil chemotaxis positive regulation of inflammatory response positive regulation of eosinophil migration
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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