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  • Primary Antibodies ›
  • PMSCL1 Antibodies

Proteintech

EXOSC9 Polyclonal Antibody

1 Reference
View all (9) PMSCL1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite EXOSC9 Polyclonal Antibody

  • Antibody Testing Data (7)
EXOSC9 Antibody in Immunocytochemistry (ICC/IF)
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EXOSC9 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 7

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EXOSC9 Antibody (24470-1-AP) in ICC/IF

Immunofluorescent analysis of HeLa cells using 24470-1-AP (EXOSC9 antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IGG. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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EXOSC9 Antibody in Immunocytochemistry (ICC/IF)
EXOSC9 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
EXOSC9 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
EXOSC9 Antibody in Western Blot (WB)
EXOSC9 Antibody in Western Blot (WB)
EXOSC9 Antibody in Western Blot (WB)
EXOSC9 Antibody in Western Blot (WB)
EXOSC9 Polyclonal Antibody

Product Details

24470-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

1:10-1:100
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

EXOSC9 Fusion Protein Ag19768 (1-351 aa encoded by BC142978)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MKETPLSNC ERRFLLRAIE EKKRLDGRQT YDYRNIRISF GTDYGCCIVE LGKTRVLGQV SCELVSPKLN RATEGILFFN LELSQMAAPA FEPGRQSDLL VKLNRLMERC LRNSKCIDTE SLCVVAGEKV WQIRVDLHLL NHDGNIIDAA SIAAIVALCH FRRPDVSVQG DEVTLYTPEE RDPVPLSIHH MPICVSFAFF QQGAYLLVDP NEREERVMDG LLVIAMNKHR EICTIQSSGG IMLLKDQVLR CSKIAGVKVA EITELILKAL ENDQKVRKEG GKFGFAESIA NQRITAFKME KAPIDTSDVE EKAEEIIAEA EPPSEVVSTP VLWTPGTAQI GEGVENSWGD LE (1-351 aa encoded by BC142978)

Target Information

This gene encodes a component of the human exosome, a exoribonuclease complex which processes and degrades RNA in the nucleus and cytoplasm. This component may play a role in mRNA degradation and the polymyositis/scleroderma autoantigen complex. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Autoantigen PM/Scl 1; Exosome complex component RRP45; exosome complex exonuclease RRP45; Exosome component 9; P75 polymyositis-scleroderma overlap syndrome associated autoantigen; P75 polymyositis-scleroderma overlap syndrome-associated autoantigen; PM/Scl-75; PMSCL autoantigen, 75kD; Polymyositis/scleroderma autoantigen 1; polymyositis/scleroderma autoantigen 1, 75kDa; Polymyositis/scleroderma autoantigen 75 kDa

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Gene Aliases: EXOSC9; p5; p6; PM/Scl-75; PMSCL1; RRP45; Rrp45p

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UniProt ID: (Human) Q06265, (Mouse) Q9JHI7

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Entrez Gene ID: (Human) 5393, (Mouse) 50911

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Function(s)
3'-5'-exoribonuclease activity RNA binding exoribonuclease activity protein binding AU-rich element binding poly(A) RNA binding nuclease activity exonuclease activity hydrolase activity
Process(es)
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nuclear-transcribed mRNA catabolic process rRNA processing immune response positive regulation of cell growth nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' U1 snRNA 3'-end processing U4 snRNA 3'-end processing U5 snRNA 3'-end processing regulation of mRNA stability exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay nuclear mRNA surveillance nuclear polyadenylation-dependent rRNA catabolic process nuclear polyadenylation-dependent tRNA catabolic process nuclear polyadenylation-dependent mRNA catabolic process
It has to be done as per old AB suggested Products section.
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