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  • EXOSC8 Antibodies

Invitrogen

EXOSC8 Monoclonal Antibody (4B3)

View all (8) EXOSC8 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite EXOSC8 Monoclonal Antibody (4B3)

  • Antibody Testing Data (1)
EXOSC8 Antibody in Immunocytochemistry (ICC/IF)
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EXOSC8 Antibody in Immunocytochemistry (ICC/IF)
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EXOSC8 Antibody (MA5-21342) in ICC/IF

Immunofluorescence analysis of HeLa cells using an anti-EXOSC8 monoclonal antibody (Product # MA5-21342). (antibody concentration 15 µg/mL). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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EXOSC8 Antibody in Immunocytochemistry (ICC/IF)
EXOSC8 Monoclonal Antibody (4B3)

Product Details

MA5-21342

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

Immunocytochemistry (ICC/IF)

10 µg/mL
-

ELISA (ELISA)

Assay-Dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

4B3

Immunogen

EXOSC8 (NP_852480.1, 177 a.a. ~ 276 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2-1.0 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2606171

Product Specific Information

Peptide Sequence: AEVNLKKKSY LNIRTHPVAT SFAVFDDTLL IVDPTGEEEH LATGTLTIVM DEEGKLCCLH KPGGSGLTGA KLQDCMSRAV TRHKEVKKLM DEVIKSMKPK

Target Information

This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CBP-interacting protein 3; Exosome complex component RRP43; exosome complex exonuclease RRP43; Exosome component 8; OIP-2; Opa interacting protein 2; Opa-interacting protein 2; p9; Ribosomal RNA-processing protein 43; RP11-421P11.3

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Gene Aliases: bA421P11.3; CIP3; EAP2; EXOSC8; OIP2; p9; PCH1C; RRP43; Rrp43p

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UniProt ID: (Human) Q96B26

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Entrez Gene ID: (Human) 11340

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Function(s)
exoribonuclease activity protein binding AU-rich element binding
Process(es)
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA processing biological_process nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' U1 snRNA 3'-end processing U4 snRNA 3'-end processing U5 snRNA 3'-end processing regulation of mRNA stability exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay nuclear mRNA surveillance nuclear polyadenylation-dependent rRNA catabolic process nuclear polyadenylation-dependent tRNA catabolic process nuclear polyadenylation-dependent mRNA catabolic process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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