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ESM1 Monoclonal Antibody (6D4)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ESM1 Monoclonal Antibody (6D4)

  • Antibody Testing Data (3)
ESM1 Antibody in ELISA (ELISA)
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ESM1 Antibody in ELISA (ELISA)
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ESM1 Antibody (H00011082-M02) in ELISA

Detection limit for recombinant GST tagged ESM1 is approximately 0.03 ng/mL as a capture antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ESM1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ESM1 Antibody in Western Blot (WB)
ESM1 Antibody in ELISA (ELISA)
ESM1 Monoclonal Antibody (6D4)

Product Details

H00011082-M02

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL
-

ELISA (ELISA)

0.03 ng/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

6D4

Immunogen

ESM1 (NP_008967, 85 a.a. approximately 184 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: PSNGEDPFGE EFGICKDCPY GTFGMDCRET CNCQSGICDR GTGKCLKFPF FQYSVTKSSN RFVSLTEHDM ASGDGNIVRE EVVKENAAGS PVMRKWLNPR

Target Information

Endothelial cell-specific molecule 1 is a protein that in humans is encoded by the ESM1 gene. This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Endothelial cell-specific molecule 1; ESM-1; IGFBP-rp6

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Gene Aliases: endocan; ESM1

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UniProt ID: (Human) Q9NQ30

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Entrez Gene ID: (Human) 11082

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Function(s)
hepatocyte growth factor receptor binding integrin binding insulin-like growth factor binding
Process(es)
angiogenesis regulation of cell growth sprouting angiogenesis positive regulation of cell proliferation positive regulation of hepatocyte growth factor receptor signaling pathway
It has to be done as per old AB suggested Products section.
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