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  • ERp57 Antibodies

Invitrogen

ERp57 Monoclonal Antibody (OTI3H5)

View all (41) ERp57 antibodies

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Datasheet
Protocols
Questions & Answers

Cite ERp57 Monoclonal Antibody (OTI3H5)

  • Antibody Testing Data (9)
ERp57 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ERp57 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 9

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ERp57 Antibody (MA5-26028) in IHC (P)

Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, 10mM citric buffer, pH6.0, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a PDIA3 monoclonal antibody (Product # MA5-26028). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ERp57 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERp57 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERp57 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERp57 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERp57 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERp57 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERp57 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERp57 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERp57 Antibody in Western Blot (WB)
ERp57 Monoclonal Antibody (OTI3H5)

Product Details

MA5-26028

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

OTI3H5

Immunogen

Human recombinant protein fragment corresponding to amino acids 140-505 of PDIA3 produced in E.coli
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2724267

Target Information

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 58 kDa glucose-regulated protein; 58 kDa microsomal protein; Disulfide isomerase ER-60; endoplasmic reticulum P58; Endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ERp 57; glucose regulated protein, 58kDa; GRP 57; GRP 58; p58; PDIA 3; phospholipase C-alpha; PI PLC; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; Protein disulfide-isomerase A3

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Gene Aliases: ER60; ERP57; ERP60; ERp61; GRP57; GRP58; HEL-S-269; HEL-S-93n; HsT17083; P58; PDIA3; PI-PLC

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UniProt ID: (Human) P30101

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Entrez Gene ID: (Human) 2923

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Function(s)
protein disulfide isomerase activity cysteine-type endopeptidase activity phospholipase C activity protein binding disulfide oxidoreductase activity poly(A) RNA binding
Process(es)
antigen processing and presentation of peptide antigen via MHC class I protein folding proteolysis protein import into nucleus protein retention in ER lumen signal transduction protein folding in endoplasmic reticulum response to endoplasmic reticulum stress cell redox homeostasis oxidation-reduction process positive regulation of extrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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