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  • Erbin Antibodies

Proteintech

ERBB2IP Polyclonal Antibody

5 References
View all (14) Erbin antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ERBB2IP Polyclonal Antibody

  • Antibody Testing Data (9)
ERBB2IP Antibody in Immunocytochemistry (ICC/IF)
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ERBB2IP Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 9

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ERBB2IP Antibody (22438-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed MCF-7 cells using 22438-1-AP (ERBB2IP antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ERBB2IP Antibody in Immunocytochemistry (ICC/IF)
ERBB2IP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERBB2IP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERBB2IP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERBB2IP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERBB2IP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ERBB2IP Antibody in Western Blot (WB)
ERBB2IP Antibody in Western Blot (WB)
ERBB2IP Antibody in Western Blot (WB)
ERBB2IP Polyclonal Antibody

Product Details

22438-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
View 2 publications 2 publications

Immunohistochemistry (IHC)

-
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:500
-

Miscellaneous PubMed (MISC)

-
View 1 publication 1 publication

Not applicable (N/A)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ERBB2IP Fusion Protein Ag18206 (461-810 aa encoded by BC115012)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.47 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: AFECDEDKD EREAPPREGN LKRYPTPYPD ELKNMVKTVQ TIVHRLKDEE TNEDSGRDLK PHEDQQDINK DVGVKTSEST TTVKSKVGER EKYMIGNSVQ KISEPEAEIS PGSLPVTANM KASENLKHIV NHDDVFEESE ELSSDEEMKM AEMRPPLIET SINQPKVVAL SNNKKDDTKE TDSLSDEVTH NSNQNNSNCS SPSRMSDSVS LNTDSSQDTS LCSPVKQTHI DINSKIRQED ENFNSLLQNG DILNSSTEEK FKAHDKKDFN LPEYDLNVEE RLVLIEKSVD STATADDTHK LDHINMNLNK LITNDTFQPE IMERSKTQDI VLGTSFLSIN SKEETEHLEN G (461-810 aa encoded by BC115012)

Target Information

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Densin-180-like protein; epididymis secretory protein Li 78; Erbb2-interacting protein; Erbin; Protein LAP2

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Gene Aliases: ERBB2IP; ERBIN; HEL-S-78; KIAA1225; LAP2

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UniProt ID: (Human) Q96RT1

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Entrez Gene ID: (Human) 55914

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Function(s)
receptor binding ErbB-2 class receptor binding integrin binding structural constituent of cytoskeleton protein binding
Process(es)
protein targeting cell cycle cell adhesion signal transduction epidermal growth factor receptor signaling pathway integrin-mediated signaling pathway cell growth negative regulation of NF-kappaB transcription factor activity response to muramyl dipeptide response to lipopolysaccharide ERBB2 signaling pathway intermediate filament cytoskeleton organization basal protein localization establishment or maintenance of epithelial cell apical/basal polarity negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway cellular response to tumor necrosis factor negative regulation of monocyte chemotactic protein-1 production
It has to be done as per old AB suggested Products section.
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