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Abnova
EPHA5 Monoclonal Antibody (5C8)
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Product Details
H00002044-M04
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Product Specific Information
Sequence of this protein is as follows: PSVVRHLAVF PDTITGADSS QLLEVSGSCV NHSVTDEPPK MHCSAEGEWL VPIGKCMCKA GYEEKNGTCQ VCRPGFFKAS PHIQSCGKCP PHSYTHEEAS
Target Information
EPHA5 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e. g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e. g. ABL, FAK, JAK, and SRC families).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ARCC2; Brain-specific kinase; CTPA; CTPP1; ECK; EHK-1; EK7; epa5; EPH homology kinase 1; EPH-like kinase 7; Ephrin A2; Ephrin A5; Ephrin type-A receptor 5; EphrinA2; EphrinA5; receptor protein-tyrosine kinase HEK7; tyrosine-protein kinase receptor EHK-1
Gene Aliases: BSK; CEK7; EHK-1; EHK1; EK7; EPHA5; HEK7; TYRO4
UniProt ID: (Human) P54756
Entrez Gene ID: (Human) 2044
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