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  • Primary Antibodies ›
  • Neutrophil elastase Antibodies

Abnova

ELA2 Monoclonal Antibody (4E12)

View all (30) Neutrophil elastase antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ELA2 Monoclonal Antibody (4E12)

ELA2 Monoclonal Antibody (4E12)

Product Details

H00001991-M04C

Applications
Tested Dilution
Publications

ELISA (ELISA)

0.3 ng/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

4E12

Immunogen

ELA2 (NP_001963, 168 a.a. approximately 267 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

tissue culture supernatant

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: VLQELNVTVV TSLCRRSNVC TLVRGRQAGV CFGDSGSPLV CNGLIHGIAS FVRGGCASGL YPDAFAPVAQ FVNWIDSIIQ RSEDNPCPHP RDPDPASRTH

Target Information

The neutrophil form of elastase is 218 amino acids long, with two asparagine-linked carbohydrate chains (see glycosylation). It is present in azurophil granules in the neutrophil cytoplasm. There appear to be two forms of neutrophil elastase, termed IIa and IIb.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Bone marrow serine protease; ELA2A; Elastase; elastase 2, neutrophil; Elastase-2; Elastase2; granulocyte-derived elastase; HLE; Human leukocyte elastase; leukocyte elastase; Medullasin; Neutrophil elastase; PE-1; PMN elastase; polymorphonuclear elastase

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Gene Aliases: ELA2; ELANE; GE; HLE; HNE; NE; PMN-E; SCN1

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UniProt ID: (Human) P08246

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Entrez Gene ID: (Human) 1991

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Function(s)
RNA polymerase II transcription corepressor activity protease binding endopeptidase activity serine-type endopeptidase activity protein binding heparin binding peptidase activity cytokine binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter response to yeast acute inflammatory response to antigenic stimulus proteolysis cellular calcium ion homeostasis phagocytosis response to UV extracellular matrix disassembly protein catabolic process response to lipopolysaccharide defense response to bacterium positive regulation of MAP kinase activity negative regulation of growth of symbiont in host negative regulation of chemokine biosynthetic process negative regulation of interleukin-8 biosynthetic process positive regulation of interleukin-8 biosynthetic process positive regulation of smooth muscle cell proliferation negative regulation of inflammatory response positive regulation of immune response leukocyte migration negative regulation of chemotaxis neutrophil mediated killing of fungus
It has to be done as per old AB suggested Products section.
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