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  • EDA Antibodies

Abnova

EDA Monoclonal Antibody (1E2)

View all (19) EDA antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite EDA Monoclonal Antibody (1E2)

EDA Monoclonal Antibody (1E2)

Product Details

H00001896-M09

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

ELISA (ELISA)

10 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

1E2

Immunogen

EDA (NP_001390.1, 245 a.a. approximately 391 a.a) partial recombinant protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: ENQPAVVHLQ GQGSAIQVKN DLSGGVLNDW SRITMNPKVF KLHPRSGELE VLVDGTYFIY SQVEVYYINF TDFASYEVVV DEKPFLQCTR SIETGKTNYN TCYTAGVCLL KARQKIAVKM VHADISINMS KHTTFFGAIR LGEAPAS

Target Information

EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. This protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in the gene for EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Ectodermal dysplasia protein; Ectodysplasin; Ectodysplasin-A; EDA 1; EDA protein; oligodontia 1; tumor necrosis factor ligand 7C; X-linked anhidroitic ectodermal dysplasia protein

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Gene Aliases: ECTD1; ED1; ED1-A1; ED1-A2; EDA; EDA-A1; EDA-A2; EDA1; EDA2; HED; HED1; ODT1; STHAGX1; TNLG7C; XHED; XLHED

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UniProt ID: (Human) Q92838

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Entrez Gene ID: (Human) 1896

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Function(s)
receptor binding tumor necrosis factor receptor binding protein binding
Process(es)
immune response cell-matrix adhesion gene expression positive regulation of gene expression cell differentiation tumor necrosis factor-mediated signaling pathway positive regulation of NF-kappaB import into nucleus odontogenesis of dentin-containing tooth pigmentation positive regulation of NF-kappaB transcription factor activity salivary gland cavitation hair follicle placode formation trachea gland development positive regulation of canonical Wnt signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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