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  • Primary Antibodies ›
  • DRD1 Antibodies

Fabgennix

Dopamine Receptor D1 Polyclonal Antibody, FITC

View all (30) DRD1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Dopamine Receptor D1 Polyclonal Antibody, FITC

Dopamine Receptor D1 Polyclonal Antibody, FITC

Product Details

D1R-C-FITC

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (IHC)

1:50-1:250
-

Immunocytochemistry (ICC/IF)

1:50-1:250
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-

Immunomicroscopy (IM)

1:50-1:200
-
Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken within amino acid region 250-300 on mouse D(1A) dopamine receptor.
View immunogen

Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra spectra

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: D(1A) dopamine receptor; D1 receptor; D1A dopamine receptor; D1a receptor; Dopamine 1 receptor; Dopamine D1 receptor; dopamine receptor D1A; Dopamine-1A receptor; G protein-coupled receptor DRD1

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Gene Aliases: C030036C15Rik; D1a; Drd-1; Drd1; Drd1a; Gpcr15

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UniProt ID: (Mouse) Q61616

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Entrez Gene ID: (Mouse) 13488, (Rat) 24316

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Function(s)
dopamine neurotransmitter receptor activity, coupled via Gs G-protein alpha-subunit binding signal transducer activity G-protein coupled receptor activity dopamine neurotransmitter receptor activity receptor binding protein binding drug binding G-protein coupled amine receptor activity protein phosphatase binding angiotensin receptor binding D3 dopamine receptor binding protein complex binding dopamine binding protein heterodimerization activity ATPase binding
Process(es)
temperature homeostasis conditioned taste aversion behavioral fear response synaptic transmission, dopaminergic startle response response to amphetamine negative regulation of protein kinase activity protein import into nucleus intracellular protein transport muscle contraction signal transduction G-protein coupled receptor signaling pathway G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger adenylate cyclase-activating G-protein coupled receptor signaling pathway activation of adenylate cyclase activity adenylate cyclase-activating dopamine receptor signaling pathway dopamine receptor signaling pathway chemical synaptic transmission sensory perception of chemical stimulus learning memory mating behavior grooming behavior locomotory behavior adult walking behavior feeding behavior associative learning visual learning positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway astrocyte development dopamine transport transmission of nerve impulse neuronal action potential regulation of vasoconstriction calcium-mediated signaling dentate gyrus development striatum development hippocampus development cerebral cortex GABAergic interneuron migration positive regulation of cell migration negative regulation of cell migration peristalsis positive regulation of cAMP biosynthetic process phosphatidylinositol catabolic process operant conditioning social behavior regulation of dopamine metabolic process response to cocaine vasodilation negative regulation of circadian sleep/wake cycle, sleep response to drug maternal behavior regulation of ion transport positive regulation of adenylate cyclase activity positive regulation of membrane potential glucose import phosphatidylinositol metabolic process habituation sensitization behavioral response to cocaine regulation of long-term neuronal synaptic plasticity positive regulation of release of sequestered calcium ion into cytosol positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway positive regulation of synaptic transmission, glutamatergic prepulse inhibition phospholipase C-activating dopamine receptor signaling pathway long-term synaptic potentiation long term synaptic depression cellular response to catecholamine stimulus positive regulation of long-term synaptic potentiation positive regulation of feeding behavior synapse assembly response to organonitrogen compound response to organic cyclic compound response to activity orbitofrontal cortex development response to food response to estradiol response to retinoic acid cellular response to insulin stimulus response to nicotine response to antidepressant response to amino acid response to morphine response to ethanol response to steroid hormone cellular response to hypoxia
It has to be done as per old AB suggested Products section.
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