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  • Primary Antibodies ›
  • DRD5 Antibodies

Fabgennix

Dopamine D5 Receptor Polyclonal Antibody

View all (15) DRD5 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Dopamine D5 Receptor Polyclonal Antibody

Product Details

D5R-512AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Human, Non-human primate, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to unique sequence on Dopamine Receptor D5 protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Target Information

The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: D(1B) dopamine receptor; D(5) dopamine receptor; D1b receptor; D1beta dopamine receptor; Dopamine 5 receptor; Dopamine D5 receptor; dopamine receptor 5; dopamine receptor D1B; DRD 1B; DRD 5; Hd5dr; MGC10601

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Gene Aliases: D1B; DBDR; DRD1B; DRD1L2; DRD5

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UniProt ID: (Human) P21918, (Rat) P25115

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Entrez Gene ID: (Human) 1816, (Rat) 25195

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Function(s)
dopamine neurotransmitter receptor activity, coupled via Gs dopamine neurotransmitter receptor activity dopamine binding G-protein alpha-subunit binding protein binding drug binding
Process(es)
synaptic transmission, dopaminergic response to amphetamine regulation of systemic arterial blood pressure by vasopressin norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure cellular calcium ion homeostasis adenylate cyclase-activating G-protein coupled receptor signaling pathway activation of adenylate cyclase activity adenylate cyclase-activating dopamine receptor signaling pathway chemical synaptic transmission learning associative learning positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway transmission of nerve impulse negative regulation of NAD(P)H oxidase activity wound healing response to cocaine positive regulation of adenylate cyclase activity negative regulation of blood pressure regulation of female receptivity sensitization phospholipase C-activating dopamine receptor signaling pathway long term synaptic depression cellular response to catecholamine stimulus reactive oxygen species metabolic process negative regulation of protein kinase activity dopamine receptor signaling pathway mating behavior visual learning negative regulation of cell migration positive regulation of cAMP biosynthetic process regulation of long-term neuronal synaptic plasticity
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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