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  • Primary Antibodies ›
  • Desmoglein 2 (DSG2) Antibodies

AbboMax

Desmoglein 2 Monoclonal Antibody (ZY50)

View all (32) Desmoglein 2 (DSG2) antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Desmoglein 2 Monoclonal Antibody (ZY50)

  • Antibody Testing Data (1)
Desmoglein 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Desmoglein 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Desmoglein 2 Antibody (605-770) in IHC (P)

Immunohistochemistry: Human GIST carcinoma (FFPE) stained with Mouse anti-Desmoglein 2 (Clone ZY50) (Cat# 605-770) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Desmoglein 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

605-770

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

2-10 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

ZY50

Immunogen

A partial recombinant protein of human Desmoglein 2

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS with proprietary stabilizer

Contains

0.01% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Product Specific Information

Positive control: Human thyroid gland papillary carcinoma

Cellular location: Cell membrane, Cell junction.

Target Information

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ARVC10; ARVD10; Cadherin family member 5; CMD1BB; Desmoglein-2; DSG-2; HDGC; MGC117034; MGC117036; MGC117037

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Gene Aliases: CDHF5; DSG2; HDGC

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UniProt ID: (Human) Q14126

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Entrez Gene ID: (Human) 1829

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Function(s)
calcium ion binding cell adhesion molecule binding cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
Process(es)
desmosome organization Purkinje myocyte development cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules response to progesterone maternal process involved in female pregnancy bundle of His cell-Purkinje myocyte adhesion involved in cell communication regulation of heart rate by cardiac conduction regulation of ventricular cardiac muscle cell action potential
It has to be done as per old AB suggested Products section.
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