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  • Desmoglein 2 (DSG2) Antibodies

Bioss

Desmoglein 2 Polyclonal Antibody

View all (32) Desmoglein 2 (DSG2) antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite Desmoglein 2 Polyclonal Antibody

  • Antibody Testing Data (2)
Desmoglein 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Desmoglein 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Desmoglein 2 Antibody (BS-10152R) in IHC (P)

Paraformaldehyde-fixed, paraffin embedded Mouse kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with Desmoglein 2 Polyclonal Antibody, Unconjugated (bs-10152R) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody and... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Desmoglein 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Desmoglein 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Desmoglein 2 Polyclonal Antibody

Product Details

BS-10152R

Applications
Tested Dilution
Publications

Western Blot (WB)

Assay-dependent
-

Immunohistochemistry (Paraffin) (IHC (P))

1:400
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Desmoglein 2, amino acids 51-150.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ARVC10; ARVD10; Cadherin family member 5; CMD1BB; desmoglein 2; Desmoglein-2; DSG-2; HDGC; MGC117034; MGC117036; MGC117037

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Gene Aliases: AA408168; CDHF5; D18Ertd293e; DSG2; HDGC

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UniProt ID: (Human) Q14126, (Mouse) O55111

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Entrez Gene ID: (Human) 1829, (Mouse) 13511, (Rat) 307562

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Function(s)
calcium ion binding cell adhesion molecule binding cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication metal ion binding
Process(es)
desmosome organization Purkinje myocyte development cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules response to progesterone maternal process involved in female pregnancy bundle of His cell-Purkinje myocyte adhesion involved in cell communication regulation of heart rate by cardiac conduction regulation of ventricular cardiac muscle cell action potential ventricular cardiac muscle cell action potential bundle of His cell to Purkinje myocyte communication
It has to be done as per old AB suggested Products section.
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