Invitrogen

Desmoglein 1 Polyclonal Antibody

Name: Desmoglein 1 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-112075

View all (27) Desmoglein 1 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)

Desmoglein 1 Antibody in Western Blot (WB)

FIGURE: 1 / 1

Desmoglein 1 Antibody (PA5-112075) in WB

Western Blot analysis of Desmoglein 1 using Desmoglein 1 Polyclonal Antibody (Product # PA5-112075) at a dilution of 1:500. Lane A: Jurkat whole cell lysate, Lane B: K562 whole cell lysate, Lane C: 293 whole cell lysate, (Lysates/proteins at 30 µg per lane). The secondary antibody used was a Goat Anti-Rabbit IgG H&L (Dylight 800) at 1:10,000 dilution. Developed using the Odyssey technique and performed under reducing conditions Predicted band size: 114 kDa. Observed band size: 114 kDa (We are unsure as to the identity of these extra bands)... View More

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Product Details

PA5-112075

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to the center region of the Human DSG1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2866811

Target Information

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cadherin family member 4; Desmoglein-1; Desmosomal glycoprotein 1; DG1; Pemphigus foliaceus antigen

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Gene Aliases: CDHF4; DG1; DSG; DSG1; EPKHE; EPKHIA; PPKS1; SPPK1

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UniProt ID: (Human) Q02413

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Entrez Gene ID: (Human) 1828

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Function(s)

calcium ion binding protein binding toxic substance binding gamma-catenin binding

Process(es)

cell-cell junction assembly homophilic cell adhesion via plasma membrane adhesion molecules single organismal cell-cell adhesion calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules response to progesterone protein stabilization maternal process involved in female pregnancy

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Desmoglein 1 Polyclonal Antibody

Desmoglein 1 Antibody (PA5-112075) in WB

Product Details

PA5-112075

Western Blot (WB)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

References (0)

Bioinformatics

Performance Guarantee

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