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  • Primary Antibodies ›
  • Desmoglein 1 Antibodies

Bioss

Desmoglein 1 Polyclonal Antibody

View all (27) Desmoglein 1 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Desmoglein 1 Polyclonal Antibody

Desmoglein 1 Polyclonal Antibody

Product Details

BS-6725R

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Desmoglein 1, amino acids 51-150.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cadherin family member 4; desmoglein 1; desmoglein 1 beta; desmoglein 1 gamma; Desmoglein-1; Desmosomal glycoprotein 1; DG1; Pemphigus foliaceus antigen

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Gene Aliases: CDHF4; DG1; DSG; DSG1; Dsg1b; Dsg1c; EPKHE; EPKHIA; PPKS1; SPPK1

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UniProt ID: (Human) Q02413

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Entrez Gene ID: (Human) 1828, (Rat) 291755

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Function(s)
calcium ion binding protein binding toxic substance binding gamma-catenin binding molecular_function
Process(es)
cell-cell junction assembly homophilic cell adhesion via plasma membrane adhesion molecules single organismal cell-cell adhesion calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules response to progesterone protein stabilization maternal process involved in female pregnancy
It has to be done as per old AB suggested Products section.
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