Invitrogen

Desmocollin 2 Polyclonal Antibody

Name: Desmocollin 2 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-81600

View all (20) Desmocollin 2 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)

Desmocollin 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 1

Desmocollin 2 Antibody (PA5-81600) in IHC (P)

Immunohistochemical staining of rat Desmocollin 2 in rat heart with Desmocollin 2 Polyclonal Antibody (Product # PA5-81600, 1:5,000, formalin-fixed paraffin embedded sections).

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Product Details

PA5-81600

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:2,500-1:10,000

ELISA (ELISA)

1:5,000-1:10,000

Product Specifications

Species Reactivity

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Rat DSC2 protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2788798

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Rat DSC2.

Target Information

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ARVC10; ARVD10; CDHF5; CDHF6; CMD1BB; desmocollin-2; desmoglein-2; desmoglein-3; HDGC; PVA

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Entrez Gene ID: (Rat) 291760