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NeoBiotechnologies
Desmocollin-2/3 Monoclonal Antibody (rDSC2/3437)
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Product Details
1824-MSM2-P1ABX
Species Reactivity
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Conjugate
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Target Information
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ARVC10; ARVD10; Cadherin family member 2; Cadherin family member 3; CDHF5; CDHF6; CMD1BB; Desmocollin-2; Desmocollin-3; Desmocollin-4; desmoglein-2; desmoglein-3; Desmosomal glycoprotein II; desmosomal glycoprotein II/III; Desmosomal glycoprotein III; Epithelial type 2 desmocollin; HDGC; HT-CP; PVA
Gene Aliases: 5430426I24Rik; ARVD11; AW228162; CDHF2; CDHF3; DG2; DGII/III; DSC; DSC1; DSC2; Dsc2a; Dsc2b; DSC3; DSC4; HT-CP
UniProt ID: (Human) Q02487, (Human) Q14574, (Mouse) P55292, (Mouse) P55850
Entrez Gene ID: (Human) 1824, (Human) 1825, (Rat) 291760, (Mouse) 13506, (Mouse) 13507, (Rat) 307563
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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