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  • Primary Antibodies ›
  • DOM3Z Antibodies

Invitrogen

DOM3Z Polyclonal Antibody

View all (20) DOM3Z antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite DOM3Z Polyclonal Antibody

  • Antibody Testing Data (6)
DOM3Z Antibody in Immunocytochemistry (ICC/IF)
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DOM3Z Antibody in Immunocytochemistry (ICC/IF)
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DOM3Z Antibody (PA5-100141) in ICC/IF

Immunofluorescent analysis of DOM3Z in HUVEC cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and DOM3Z polyclonal antibody (Product # PA5-100141) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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DOM3Z Antibody in Immunocytochemistry (ICC/IF)
DOM3Z Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DOM3Z Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DOM3Z Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DOM3Z Antibody in Western Blot (WB)
DOM3Z Antibody in Western Blot (WB)
DOM3Z Polyclonal Antibody

Product Details

PA5-100141

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human DXO(Accession O77932), corresponding to amino acid residues A66-R116.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2815671

Product Specific Information

Antibody detects endogenous levels of total DOM3Z.

Target Information

This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. The function of its protein product is unknown, but its ubiquitous expression and conservation in both simple and complex eukaryotes suggests that this may be a housekeeping gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 5'-3' exoribonuclease DXO; Decapping and exoribonuclease protein; DeNADding enzyme DXO; Dom-3 homolog Z; DXO; NAD-capped RNA hydrolase DXO; protein Dom3Z

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Gene Aliases: DOM3L; DOM3Z; DXO; NG6; RAI1

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UniProt ID: (Human) O77932, (Rat) Q6MG77, (Mouse) O70348

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Entrez Gene ID: (Human) 1797, (Rat) 361799, (Mouse) 112403

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Function(s)
nucleotide binding magnesium ion binding mRNA binding 5'-3' exonuclease activity RNA pyrophosphohydrolase activity molecular_function 3'-5'-exoribonuclease activity RNA binding nuclease activity exonuclease activity 5'-3' exoribonuclease activity thiamine-pyrophosphatase activity 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity UDP-2,3-diacylglucosamine hydrolase activity bis(5'-nucleosyl)-tetraphosphatase activity dATP pyrophosphohydrolase activity pyrophosphatase activity hydrolase activity dihydroneopterin monophosphate phosphatase activity dihydroneopterin triphosphate pyrophosphohydrolase activity dITP diphosphatase activity dTTP diphosphatase activity XTP diphosphatase activity ATP-dependent 5'-3' DNA helicase activity phosphocholine hydrolase activity metal ion binding
Process(es)
mRNA catabolic process biological_process metabolic process RNA destabilization nuclear mRNA surveillance nucleic acid phosphodiester bond hydrolysis
It has to be done as per old AB suggested Products section.
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