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  • DNAJB6 Antibodies

Invitrogen

DNAJB6 Polyclonal Antibody

View all (28) DNAJB6 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite DNAJB6 Polyclonal Antibody

  • Antibody Testing Data (4)
DNAJB6 Antibody in Immunocytochemistry (ICC/IF)
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DNAJB6 Antibody in Immunocytochemistry (ICC/IF)
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DNAJB6 Antibody (PA5-121060) in ICC/IF

Immunofluorescence analysis of DNAJB6 in U2OS cells. Samples were incubated with DNAJB6 Polyclonal antibody (Product # PA5-121060). Blue: DAPI for nuclear staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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DNAJB6 Antibody in Immunocytochemistry (ICC/IF)
DNAJB6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DNAJB6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DNAJB6 Antibody in Western Blot (WB)
DNAJB6 Polyclonal Antibody

Product Details

PA5-121060

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:100
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 177-326 of human DNAJB6 (NP_490647.1).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.96 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914632

Product Specific Information

Positive test controls include: SW480, MCF7, 293T, Jurkat, HeLa, Mouse testis, Mouse brain, Rat brain. The target is usually found in the following locations: Cytoplasm, Nucleus, Z line, myofibril, perinuclear region, sarcomere.

Immunogen sequence: STSFGGSGMG NFKSISTSTK MVNGRKITTK RIVENGQERV EVEEDGQLKS LTINGVADDD ALAEERMRRG QNALPAQPAG LRPPKPPRPA SLLRHAPHCL SEEEGEQDRP RAPGPWDPLA SAAGLKEGGK RKKQKQREES KKKKSTKGNH

Target Information

This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DnaJ (Hsp40) homolog, subfamily B, member 6; DnaJ homolog subfamily B member 6; DnaJ-like 2 protein; dnajb6 {ECO:0000312|EMBL:AAH78908.1, ECO:0000312|RGD:1308207}; Heat shock protein J2; HHDJ1; HSJ-2; Hsp40 homolog; mammalian relative of DnaJ; mDj4; MRJ; MSJ-1

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Gene Aliases: DJ4; DnaJ; DNAJB6; HHDJ1; HSJ-2; HSJ2; LGMD1D; LGMD1E; mDj4; MRJ; MSJ-1; MSJ1

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UniProt ID: (Human) O75190, (Mouse) O54946, (Rat) Q6AYU3

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Entrez Gene ID: (Human) 10049, (Mouse) 23950, (Rat) 362293

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Function(s)
ATPase activator activity DNA binding protein binding heat shock protein binding unfolded protein binding chaperone binding protein binding involved in protein folding
Process(es)
protein folding actin cytoskeleton organization extracellular matrix organization positive regulation of ATPase activity regulation of protein localization protein localization to nucleus negative regulation of cysteine-type endopeptidase activity involved in apoptotic process intermediate filament organization negative regulation of transcription, DNA-templated chorio-allantoic fusion syncytiotrophoblast cell differentiation involved in labyrinthine layer development chorion development negative regulation of inclusion body assembly regulation of cellular response to heat chaperone-mediated protein folding
It has to be done as per old AB suggested Products section.
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