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Invitrogen
DNA Ligase III Monoclonal Antibody (1F3)
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FIGURE: 1 / 5
DNA Ligase III Antibody (MA1-23191) in WB
Product Details
MA1-23191
Species Reactivity
Published species
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Conjugate
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Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2.
The predicted molecular weight of MA1-23191 is 100 kDa.
Target Information
There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100 kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97 kDa (beta form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DNA ligase (ATP) 3; DNA ligase 3; DNA ligase III; ligase II, DNA, ATP-dependent; ligase III, DNA, ATP-dependent; Polydeoxyribonucleotide synthase [ATP] 3
Gene Aliases: D11Wsu78e; LIG2; LIG3; RCJMB04_4j11
UniProt ID: (Human) P49916
Entrez Gene ID: (Chicken) 417530, (Human) 3980, (Mouse) 16882
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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