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OriGene

DLD Monoclonal Antibody (OTI5G7), TrueMAB™

View all (42) DLD antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite DLD Monoclonal Antibody (OTI5G7), TrueMAB™

  • Antibody Testing Data (5)
DLD Antibody in Immunocytochemistry (ICC/IF)
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DLD Antibody in Immunocytochemistry (ICC/IF)
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DLD Antibody (TA503391) in ICC/IF

Anti-DLD mouse monoclonal antibody (TA503391) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DLD(RC200639). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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DLD Antibody in Immunocytochemistry (ICC/IF)
DLD Antibody in Western Blot (WB)
DLD Antibody in Western Blot (WB)
DLD Antibody in Western Blot (WB)
DLD Antibody in Flow Cytometry (Flow)
DLD Monoclonal Antibody (OTI5G7), TrueMAB™

Product Details

TA503391

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

Immunocytochemistry (ICC/IF)

1:100
-

Flow Cytometry (Flow)

1:100
-
Product Specifications

Species Reactivity

Dog, Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI5G7

Immunogen

Full length human recombinant protein of human DLD produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.98 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: branched chain alpha-keto acid dehydrogenase complex subunit E3; diaphorase; Dihydrolipoamide dehydrogenase; dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex); dihydrolipoamide: NAD+ oxidoreductase; Dihydrolipoyl dehydrogenase, mitochondrial; E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex; Glycine cleavage system L protein; glycine cleavage system protein L; lipoamide dehydrogenase; lipoamide reductase; lipoyl dehydrogenase; OTTHUMP00000206744; OTTHUMP00000206746; OTTHUMP00000206748; OTTHUMP00000206749; PH; PHE 3

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Gene Aliases: DLD; DLDD; DLDH; E3; GCSL; LAD; PHE3

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UniProt ID: (Dog) P49819, (Human) P09622, (Rat) Q6P6R2, (Mouse) O08749

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Entrez Gene ID: (Dog) 403978, (Human) 1738, (Rat) 298942, (Mouse) 13382

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Function(s)
dihydrolipoyl dehydrogenase activity flavin adenine dinucleotide binding pyruvate dehydrogenase (NAD+) activity lipoamide binding NAD binding mercury (II) reductase activity mercury ion binding NADP binding oxidoreductase activity oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
Process(es)
cell redox homeostasis oxidation-reduction process acetyl-CoA biosynthetic process from pyruvate 2-oxoglutarate metabolic process mitochondrial electron transport, NADH to ubiquinone proteolysis gastrulation aging lipoate metabolic process regulation of membrane potential sperm capacitation detoxification of mercury ion dihydrolipoamide metabolic process pyruvate metabolic process tricarboxylic acid cycle lysine catabolic process branched-chain amino acid catabolic process regulation of acetyl-CoA biosynthetic process from pyruvate glyoxylate metabolic process mitochondrial acetyl-CoA biosynthetic process from pyruvate
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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