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DLD Monoclonal Antibody (2E7G5), CoraLite® Plus 488

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite DLD Monoclonal Antibody (2E7G5), CoraLite® Plus 488

  • Antibody Testing Data (2)
DLD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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DLD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 2

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DLD Antibody (CL48867702100UL) in IHC (P)

Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite 488 DLD antibody (Product # CL48867702100UL), Clone: 2E7G5 ) at dilution of 1:200. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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DLD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DLD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DLD Monoclonal Antibody (2E7G5), CoraLite® Plus 488

Product Details

CL48867702100UL

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2E7G5

Conjugate

CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488
  • Unconjugated
  • Request custom conjugation

Excitation/Emission Max

493/522 nm

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.5% BSA

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles, store in dark

Shipping conditions

Wet ice

Target Information

This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: branched chain alpha-keto acid dehydrogenase complex subunit E3; diaphorase; Dihydrolipoamide dehydrogenase; dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex); Dihydrolipoyl dehydrogenase, mitochondrial; E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex; Glycine cleavage system L protein; glycine cleavage system protein L; lipoamide dehydrogenase; lipoamide reductase; lipoyl dehydrogenase; OTTHUMP00000206744; OTTHUMP00000206746; OTTHUMP00000206748; OTTHUMP00000206749; PH; PHE 3

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Gene Aliases: DLD; DLDD; DLDH; E3; GCSL; LAD; PHE3

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UniProt ID: (Human) P09622, (Rat) Q6P6R2, (Mouse) O08749

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Entrez Gene ID: (Human) 1738, (Rat) 298942, (Mouse) 13382

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Function(s)
dihydrolipoyl dehydrogenase activity pyruvate dehydrogenase (NAD+) activity lipoamide binding flavin adenine dinucleotide binding NAD binding mercury (II) reductase activity mercury ion binding NADP binding oxidoreductase activity oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
Process(es)
acetyl-CoA biosynthetic process from pyruvate 2-oxoglutarate metabolic process mitochondrial electron transport, NADH to ubiquinone proteolysis gastrulation aging lipoate metabolic process regulation of membrane potential cell redox homeostasis sperm capacitation detoxification of mercury ion dihydrolipoamide metabolic process oxidation-reduction process pyruvate metabolic process tricarboxylic acid cycle lysine catabolic process branched-chain amino acid catabolic process regulation of acetyl-CoA biosynthetic process from pyruvate glyoxylate metabolic process mitochondrial acetyl-CoA biosynthetic process from pyruvate
It has to be done as per old AB suggested Products section.
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