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  • DLD Antibodies

Invitrogen

DLD Polyclonal Antibody

1 Published Figure
1 Reference
View all (42) DLD antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite DLD Polyclonal Antibody

  • Antibody Testing Data (4)
  • Published Figures (1)
DLD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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DLD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 5

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DLD Antibody (PA5-70397) in IHC (P)

Immunohistochemical analysis of DLD in paraffin-embedded human pineal tissue. Sample was probed with a DLD polyclonal antibody (Product # PA5-70397) at a dilution of 1:100. Detection was performed with a donkey anti-Rabbit Cy3 secondary antibody at a dilution of 1:200. Images were taken at 20x magnification with an exposure time of 0.5-2.0 seconds. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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DLD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DLD Antibody in Western Blot (WB)
DLD Antibody in Western Blot (WB)
DLD Antibody in Western Blot (WB)
DLD Antibody in Western Blot (WB)

Product Details

PA5-70397

Applications
Tested Dilution
Publications

Western Blot (WB)

0.2-1.0 µg/mL
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

Assay-Dependent
-
Product Specifications

Species Reactivity

Human, Rat

Published species

Virus

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

synthetic peptide directed towards the middle region of human DLD

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2688322

Product Specific Information

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%; Yeast: 86%; Zebrafish: 93%

Target Information

This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: diaphorase; Dihydrolipoamide dehydrogenase; dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex); Dihydrolipoyl dehydrogenase, mitochondrial; E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex; Glycine cleavage system L protein; glycine cleavage system protein L; lipoamide dehydrogenase; lipoamide reductase; lipoyl dehydrogenase; OTTHUMP00000206744; OTTHUMP00000206746; OTTHUMP00000206748; OTTHUMP00000206749; PH; PHE 3

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Gene Aliases: DLD; DLDD; DLDH; E3; GCSL; LAD; PHE3

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UniProt ID: (Human) P09622, (Rat) Q6P6R2

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Entrez Gene ID: (Human) 1738, (Rat) 298942

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Function(s)
dihydrolipoyl dehydrogenase activity pyruvate dehydrogenase (NAD+) activity lipoamide binding flavin adenine dinucleotide binding NAD binding mercury (II) reductase activity mercury ion binding NADP binding
Process(es)
acetyl-CoA biosynthetic process from pyruvate 2-oxoglutarate metabolic process mitochondrial electron transport, NADH to ubiquinone proteolysis gastrulation aging lipoate metabolic process regulation of membrane potential cell redox homeostasis sperm capacitation detoxification of mercury ion dihydrolipoamide metabolic process oxidation-reduction process pyruvate metabolic process tricarboxylic acid cycle lysine catabolic process branched-chain amino acid catabolic process regulation of acetyl-CoA biosynthetic process from pyruvate glyoxylate metabolic process mitochondrial acetyl-CoA biosynthetic process from pyruvate
It has to be done as per old AB suggested Products section.
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