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  • Dopamine beta Hydroxylase Antibodies

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DBH/Dopamine Beta-Hydroxylase Monoclonal Antibody (DBH/7224)

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Datasheet
Protocols
Questions & Answers

Cite DBH/Dopamine Beta-Hydroxylase Monoclonal Antibody (DBH/7224)

  • Antibody Testing Data (1)
DBH/Dopamine Beta-Hydroxylase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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DBH/Dopamine Beta-Hydroxylase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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DBH/Dopamine Beta-Hydroxylase Antibody (1621-MSM4-P1ABX) in IHC (P)

Formalin-fixed, paraffin-embedded human adrenal gland stained with Dopamine Beta-Hydroxylase Mouse Monoclonal Antibody (DBH/7224). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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DBH/Dopamine Beta-Hydroxylase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DBH/Dopamine Beta-Hydroxylase Monoclonal Antibody (DBH/7224)

Product Details

1621-MSM4-P1ABX

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2, kappa

Class

Monoclonal

Type

Antibody

Clone

DBH/7224

Immunogen

Recombinant fragment (around aa200-400) of human DBH protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Dry ice (international)

Product Specific Information

Positive Control:Human adrenal gland or adrenal pheochromocytoma.

Cellular Location: Cytoplasm.

Target Information

The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Dopamine beta-hydroxylase; dopamine beta-hydroxylase (dopamine beta-monooxygenase); Dopamine beta-monooxygenase; Dopamine-Beta-hydroxylase

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Gene Aliases: DBH; DBM

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UniProt ID: (Human) P09172

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Entrez Gene ID: (Human) 1621

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Function(s)
catalytic activity dopamine beta-monooxygenase activity copper ion binding L-ascorbic acid binding
Process(es)
cytokine production blood vessel remodeling response to amphetamine leukocyte mediated immunity chemical synaptic transmission memory locomotory behavior visual learning regulation of cell proliferation homoiothermy dopamine catabolic process norepinephrine biosynthetic process catecholamine biosynthetic process glucose homeostasis fear response maternal behavior positive regulation of vasoconstriction behavioral response to ethanol response to pain leukocyte migration oxidation-reduction process regulation of extrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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