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  • D-dimer Antibodies

OriGene

D-Dimer Monoclonal Antibody (OTI6A5), TrueMAB™

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite D-Dimer Monoclonal Antibody (OTI6A5), TrueMAB™

D-Dimer Monoclonal Antibody (OTI6A5), TrueMAB™

Product Details

CF813913

Applications
Tested Dilution
Publications

ELISA (ELISA)

1:5,000-1:10,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI6A5

Immunogen

Native Human D-Dimer protein
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

See Label

Purification

Protein A/G

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Fibrinogen is the main protein of blood coagulation system. It consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. The process of blood coagulation results in the activation of fibrinogen into fibrin by thrombin and fibrin polymerization. Fibrin clot is then digested by plasmin, and fibrin degradation products of different molecular weights are released into the bloodstream.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Fibrinogen alpha chain; fibrinogen, A alpha polypeptide; MGC119422; MGC119423; MGC119425

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Gene Aliases: FGA; Fib2

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UniProt ID: (Human) P02671

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Entrez Gene ID: (Human) 2243

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Function(s)
receptor binding structural molecule activity protein binding protein binding, bridging metal ion binding cell adhesion molecule binding
Process(es)
adaptive immune response platelet degranulation protein complex assembly acute-phase response cell-matrix adhesion signal transduction blood coagulation extracellular matrix organization plasminogen activation response to estradiol response to genistein positive regulation of heterotypic cell-cell adhesion fibrinolysis induction of bacterial agglutination response to morphine cellular protein complex assembly cellular protein metabolic process innate immune response positive regulation of vasoconstriction positive regulation of exocytosis response to cycloheximide positive regulation of protein secretion protein polymerization response to calcium ion positive regulation of ERK1 and ERK2 cascade platelet aggregation cellular response to interleukin-6 cellular response to organic cyclic compound blood coagulation, common pathway blood coagulation, fibrin clot formation positive regulation of peptide hormone secretion liver regeneration positive regulation of substrate adhesion-dependent cell spreading negative regulation of extrinsic apoptotic signaling pathway via death domain receptors cellular response to granulocyte colony-stimulating factor negative regulation of endothelial cell apoptotic process
It has to be done as per old AB suggested Products section.
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