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  • Cytokeratin 8 Antibodies

Invitrogen

Cytokeratin 8 Recombinant Rabbit Monoclonal Antibody (5K6W6)

View all (103) Cytokeratin 8 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Cytokeratin 8 Recombinant Rabbit Monoclonal Antibody (5K6W6)

  • Antibody Testing Data (1)
Cytokeratin 8 Antibody in Immunocytochemistry (ICC/IF)
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Cytokeratin 8 Antibody in Immunocytochemistry (ICC/IF)
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Cytokeratin 8 Antibody (MA5-55204) in ICC/IF

Immunocytochemistry/Immunofluorescence analysis of HeLa cells using Cytokeratin 8 Recombinant Monoclonal Antibody (Product # MA5-55204) at dilution of 1:200 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Cytokeratin 8 Antibody in Immunocytochemistry (ICC/IF)

Product Details

MA5-55204

Applications
Tested Dilution
Publications

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

5K6W6

Immunogen

Recombinant protein of human Cytokeratin 8 (KRT8).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.69 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

RRID

AB_3667449

Target Information

Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CK-8; Cytokeratin-8; K8; keratin 8, type II; Keratin, type II cytoskeletal 8; Keratin-8; Type-II keratin Kb8

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Gene Aliases: CARD2; CK-8; CK8; CYK8; K2C8; K8; KO; KRT8

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UniProt ID: (Human) P05787

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Entrez Gene ID: (Human) 3856

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Function(s)
structural molecule activity protein binding protein complex binding scaffold protein binding
Process(es)
viral process tumor necrosis factor-mediated signaling pathway sarcomere organization response to hydrostatic pressure response to other organism cell differentiation involved in embryonic placenta development extrinsic apoptotic signaling pathway hepatocyte apoptotic process
It has to be done as per old AB suggested Products section.
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