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  • Cystatin C Antibodies

Invitrogen

Cystatin C Recombinant Rabbit Monoclonal Antibody (001)

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Protocols
Questions & Answers

Cite Cystatin C Recombinant Rabbit Monoclonal Antibody (001)

  • Antibody Testing Data (2)
Cystatin C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Cystatin C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Cystatin C Antibody (MA5-29864) in IHC (P)

Immunohistochemical staining of rat Cystatin C in rat kidney with Cystatin C Recombinant Rabbit Monoclonal Antibody (1) (Product # MA5-29864, 1:200, formalin-fixed paraffin embedded sections). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Cystatin C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Cystatin C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Cystatin C Recombinant Rabbit Monoclonal Antibody (001)

Product Details

MA5-29864

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-
Product Specifications

Species Reactivity

Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

001

Immunogen

Recombinant Rat Cystatin C/CST3 protein (Met1-Ala140)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2785681

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This antibody has specificity for Rat Cystatin C/CST3.

Target Information

Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AD8; cystatin 3; Cystatin C (cysteine proteinase inhibitor); Cystatin-3; Cystatin-C; Cystatin3; CystatinC; MGC117328; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; RP23-250M11.9

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Gene Aliases: Cst3; CYSC

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UniProt ID: (Rat) P14841

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Entrez Gene ID: (Rat) 25307

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Function(s)
beta-amyloid binding protease binding endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity peptidase inhibitor activity
Process(es)
eye development response to hypoxia cell activation apoptotic process defense response response to oxidative stress brain development salivary gland development embryo implantation positive regulation of cell proliferation male gonad development response to toxic substance response to carbohydrate response to inorganic substance negative regulation of peptidase activity negative regulation of collagen catabolic process negative regulation of extracellular matrix disassembly negative regulation of endopeptidase activity response to organic cyclic compound response to nutrient levels response to estradiol regulation of tissue remodeling cellular response to oxidative stress response to drug circadian sleep/wake cycle, REM sleep regulation of programmed cell death extracellular fibril organization positive regulation of DNA replication negative regulation of proteolysis response to axon injury Sertoli cell development negative regulation of elastin catabolic process negative regulation of blood vessel remodeling negative regulation of cell death cellular response to hydrogen peroxide
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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